Cryo-EM reconstruction of SARS-CoV-2 spike in complex with TAU-2212 mAb in conformation 1
Cryo EM reconstruction of SARS-CoV-2 spike in complex with TAU-2212 mAb in conformation 2
Cryo EM reconstruction of SARS-CoV-2 spike in complex with TAU-2212 in conformation 3
Cryo EM reconstruction of SARS-CoV-2 spike in complex with TAU-2212 mAbs in conformation 5
Cryo EM map of two SARS-CoV-2 spikes in complex with TAU-2212 mAbs in conformation 5
Cryo EM structure of SARS-CoV-2 spike in complex with TAU-2212 mAbs in conformation 4
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7wcd
Q-score: 0.428
Li R, Mor M, Ma B, Clark AE, Alter J, Werbner M, Lee JC, Leibel SL, Carlin AF, Dessau M, Gal-Tanamy M, Croker BA, Xiang Y, Freund NT
Commun Biol (2022) 5 pp. 789-789 [ Pubmed: 35931732 DOI: doi:10.1038/s42003-022-03739-5 ]
- Severe acute respiratory syndrome coronavirus 2 spike bound tau-2212 mab (430 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov2 spike (Complex)
- Light chain (22 kDa, Protein from Homo sapiens)
- Huamn igg tau-2212 (Complex from Homo sapiens)
- Spike glycoprotein (136 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 6zfx
Q-score: 0.368
Sporny M, Guez-Haddad J, Khazma T, Yaron A, Dessau M, Shkolnisky Y, Mim C, Isupov MN, Zalk R, Hons M, Opatowsky Y
eLife (2020) 9 [ Pubmed: 33185189 DOI: doi:10.7554/eLife.62021 ]
- Nad(+) hydrolase sarm1 (79 kDa, Protein from Homo sapiens)
- (~{e})-4-methylnon-4-enedial (168 Da, Ligand)
- Hsarm1 (Complex from Homo sapiens)
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 6zg0
Q-score: 0.091
Sporny M, Guez-Haddad J, Khazma T, Yaron A, Dessau M, Shkolnisky Y, Mim C, Isupov MN, Zalk R, Hons M, Opatowsky Y
eLife (2020) 9 [ Pubmed: 33185189 DOI: doi:10.7554/eLife.62021 ]
- 1,2-ethanediol (62 Da, Ligand)
- Hsarm1 (Complex from Homo sapiens)
- Di(hydroxyethyl)ether (106 Da, Ligand)
- Beta-mercaptoethanol (78 Da, Ligand)
- Triethylene glycol (150 Da, Ligand)
- Nad(+) hydrolase sarm1 (79 kDa, Protein from Homo sapiens)
Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 6zg1
Q-score: 0.281
Sporny M, Guez-Haddad J, Khazma T, Yaron A, Dessau M, Shkolnisky Y, Mim C, Isupov MN, Zalk R, Hons M, Opatowsky Y
eLife (2020) 9 [ Pubmed: 33185189 DOI: doi:10.7554/eLife.62021 ]
- 1,2-ethanediol (62 Da, Ligand)
- Sterile alpha and tir motif-containing protein 1 (18 kDa, Protein from Homo sapiens)
- Hsarm1 (Complex from Homo sapiens)
- Di(hydroxyethyl)ether (106 Da, Ligand)
- Beta-mercaptoethanol (78 Da, Ligand)
- Triethylene glycol (150 Da, Ligand)