Structure of the core Vaccinia Virus DNA-dependent RNA polymerase complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6ric
Q-score: 0.562
Hillen HS, Bartuli J, Grimm C, Dienemann C, Bedenk K, Szalay AA, Fischer U, Cramer P
Cell (2019) 179 pp. 1525- [ Pubmed: 31835031 DOI: doi:10.1016/j.cell.2019.11.023 ]
- Magnesium ion (24 Da, Ligand)
- Dna-dependent rna polymerase subunit rpo7 (7 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunits (Complex from Vaccinia virus GLV-1h68)
- Zinc ion (65 Da, Ligand)
- Dna-dependent rna polymerase subunit rpo147 (146 kDa, Protein from Vaccinia virus GLV-1h68)
- Rap94 transcription factor (93 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus GLV-1h68)
- Core vaccinia dna-dependent rna polymerase complex (500 kDa, Complex)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase subunit (21 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo132 (133 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo18 (17 kDa, Protein from Vaccinia virus GLV-1h68)
Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6rid
Q-score: 0.579
Hillen HS, Bartuli J, Grimm C, Dienemann C, Bedenk K, Szalay AA, Fischer U, Cramer P
Cell (2019) 179 pp. 1525- [ Pubmed: 31835031 DOI: doi:10.1016/j.cell.2019.11.023 ]
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus GLV-1h68)
- Non-template strand dna (14 kDa, DNA from Vaccinia virus)
- Magnesium ion (24 Da, Ligand)
- Dna-dependent rna polymerase subunit rpo7 (7 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo132 (Complex from Vaccinia virus GLV-1h68)
- Zinc ion (65 Da, Ligand)
- Dna-dependent rna polymerase subunit rpo147 (146 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase subunit (21 kDa, Protein from Vaccinia virus GLV-1h68)
- Template strand dna (14 kDa, DNA from Vaccinia virus)
- Rna (9 kDa, RNA from Vaccinia virus)
- Dna-directed rna polymerase subunits (Complex from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo132 (133 kDa, Protein from Vaccinia virus GLV-1h68)
- Vaccinia virus dna-dependent rna polymerase elongation complex (450 kDa, Complex)
- Dna-dependent rna polymerase subunit rpo18 (17 kDa, Protein from Vaccinia virus GLV-1h68)
- Nucleic acids (Complex from Vaccinia virus GLV-1h68)
Structure of Vaccinia Virus DNA-dependent RNA polymerase co-transcriptional capping complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6rie
Q-score: 0.558
Hillen HS, Bartuli J, Grimm C, Dienemann C, Bedenk K, Szalay AA, Fischer U, Cramer P
Cell (2019) 179 pp. 1525- [ Pubmed: 31835031 DOI: doi:10.1016/j.cell.2019.11.023 ]
- Dna-dependent rna polymerase subunit rpo18 (17 kDa, Protein from Vaccinia virus)
- Magnesium ion (24 Da, Ligand)
- Vaccinia virus dna-dependent rna polymerase co-transcriptional capping complex (580 kDa, Complex)
- Dna-dependent rna polymerase subunit rpo7 (7 kDa, Protein from Vaccinia virus)
- Dna-dependent rna polymerase subunit rpo132 (133 kDa, Protein from Vaccinia virus)
- S-adenosylmethionine (398 Da, Ligand)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus)
- Rna (9 kDa, RNA from Vaccinia virus)
- Zinc ion (65 Da, Ligand)
- Small subunit of mrna capping enzyme (33 kDa, Protein from Vaccinia virus)
- Rna (Complex from Vaccinia virus)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus)
- Dna-dependent rna polymerase subunit rpo147 (146 kDa, Protein from Vaccinia virus)
- Large subunit of mrna capping enzyme (96 kDa, Protein from Vaccinia virus)
- Dna-directed rna polymerase 30 kda polypeptide (29 kDa, Protein from Vaccinia virus)
- Synthetic (Complex from Vaccinia virus)
- Non-template dna strand (14 kDa, DNA from Vaccinia virus)
- Dna-directed rna polymerase subunit (21 kDa, Protein from Vaccinia virus)
- Template strand dna (14 kDa, DNA from Vaccinia virus)
- Dna-dependent rna polymerase subunit (Complex from Vaccinia virus)
Hillen HS, Bartuli J, Grimm C, Dienemann C, Bedenk K, Szalay AA, Fischer U, Cramer P
Cell (2019) 179 pp. 1525-1536.e12 [ Pubmed: 31835031 DOI: doi:10.1016/j.cell.2019.11.023 ]
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6s01
Q-score: 0.529
Wang H, Farnung L, Dienemann C, Cramer P
Nat Struct Mol Biol (2020) 27 pp. 8-13 [ DOI: doi:10.1038/s41594-019-0345-4 Pubmed: 31819277 ]
- Wisdom 601 dna (165-mer) (Complex from synthetic construct)
- Histone h2a (13 kDa, Protein from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Wisdom 601 dna (165-mer) (50 kDa, DNA from synthetic construct)
- H3k36me3 nucleosome-ledgf complex (250 kDa, Complex)
- Wisdom 601 dna (165-mer) (51 kDa, DNA from synthetic construct)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Pc4 and sfrs1-interacting protein (60 kDa, Protein from Homo sapiens)
- Histone proteins (Complex from Xenopus laevis)
- Pc4 and sfrs1-interacting protein (Complex from Homo sapiens)
Structure of the complete Vaccinia DNA-dependent RNA polymerase complex
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 6rfl
Q-score: 0.572
Grimm C, Hillen HS, Bedenk K, Bartuli J, Neyer S, Zhang Q, Huttenhofer A, Erlacher M, Dienemann C, Schlosser A, Urlaub H, Bottcher B, Szalay AA, Cramer P, Fischer U
Cell (2019) 179 pp. 1537-1550.e19 [ Pubmed: 31835032 DOI: doi:10.1016/j.cell.2019.11.024 ]
- Large subunit of mrna capping enzyme (96 kDa, Protein from Vaccinia virus GLV-1h68)
- Virion core protein (14 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo147 (146 kDa, Protein from Vaccinia virus GLV-1h68)
- Complete vaccinia dna-dependent rna polymerase complex (Complex)
- Dna-directed rna polymerase subunit (21 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 19 kda subunit (19 kDa, Protein from Vaccinia virus GLV-1h68)
- Chr17.trna16-glnttg (23 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Rna (Complex from Homo sapiens)
- Nucleoside triphosphate phosphohydrolase-i (72 kDa, Protein from Vaccinia virus GLV-1h68)
- Transcription factor vetf 82kda large subunit (82 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo132 (133 kDa, Protein from Vaccinia virus GLV-1h68)
- Vaccinia dna-dependent rna polymerase complex (Complex from Vaccinia virus GLV-1H68)
- Zinc ion (65 Da, Ligand)
- Putative h4l rna polymerase-associated transcription factor rap94 (93 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 35 kda subunit (35 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-dependent rna polymerase subunit rpo18 (17 kDa, Protein from Vaccinia virus GLV-1h68)
- Water (18 Da, Ligand)
- Dna-dependent rna polymerase subunit rpo7 (7 kDa, Protein from Vaccinia virus GLV-1h68)
- Dna-directed rna polymerase 30 kda polypeptide (30 kDa, Protein from Vaccinia virus GLV-1h68)
- Small subunit of mrna capping enzyme (33 kDa, Protein from Vaccinia virus GLV-1h68)
Structure of the core TFIIH-XPA-DNA complex
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6ro4
Q-score: 0.449
Kokic G, Chernev A, Tegunov D, Dienemann C, Urlaub H, Cramer P
Nat Commun (2019) 10 pp. 2885-2885 [ DOI: doi:10.1038/s41467-019-10745-5 Pubmed: 31253769 ]
- General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
- Dna (Complex from Homo sapiens)
- Dna2 (15 kDa, DNA from Homo sapiens)
- General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
- Tfiih basal transcription factor complex helicase xpd subunit (87 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Core tfiih-xpa-dna complex (Complex)
- Dna1 (15 kDa, DNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Tfiih-xpa (Complex from Homo sapiens)
- General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
- Dna repair protein complementing xp-a cells (31 kDa, Protein from Homo sapiens)
- General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)