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author:"Dienemann C" AND xref_links:"drugbank" AND software_ft:"RELION"
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Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite map 1 for structure 2)

Release date: Oct. 18, 2023
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8oew
Q-score: 0.56

Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P

Nat Struct Mol Biol (2023) 30 pp. 1925-1935 [ DOI: doi:10.1038/s41594-023-01138-w Pubmed: 37932450 ]

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Structural organization of a late activated human spliceosome (Baqr, core region)

Release date: May 10, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7qtt
Q-score: 0.384

Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V

Nature (2023) 617 pp. 842-850 [ Pubmed: 37165190 DOI: doi:10.1038/s41586-023-06049-w ]

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Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).

Release date: May 10, 2023
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 8ch6
Q-score: 0.154

Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V

Nature (2023) 617 pp. 842-850 [ Pubmed: 37165190 DOI: doi:10.1038/s41586-023-06049-w ]

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RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)

Release date: May 3, 2023
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8bvw
Q-score: 0.234

Abril-Garrido J, Dienemann C, Grabbe F, Velychko T, Lidschreiber M, Wang H, Cramer P

Mol Cell (2023) 83 pp. 1798- [ Pubmed: 37148879 DOI: doi:10.1016/j.molcel.2023.04.011 ]

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RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)

Release date: May 3, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8byq
Q-score: 0.187

Abril-Garrido J, Dienemann C, Grabbe F, Velychko T, Lidschreiber M, Wang H, Cramer P

Mol Cell (2023) 83 pp. 1798- [ Pubmed: 37148879 DOI: doi:10.1016/j.molcel.2023.04.011 ]

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RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)

Release date: May 3, 2023
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8bz1
Q-score: 0.244

Abril-Garrido J, Dienemann C, Grabbe F, Velychko T, Lidschreiber M, Wang H, Cramer P

Mol Cell (2023) 83 pp. 1798- [ Pubmed: 37148879 DOI: doi:10.1016/j.molcel.2023.04.011 ]

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Structural basis of Integrator-mediated transcription regulation

Release date: Dec. 8, 2021
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7pks
Q-score: 0.278

Fianu I, Chen Y, Dienemann C, Dybkov O, Linden A, Urlaub H, Cramer P

Science (2021) 374 pp. 883-887 [ DOI: doi:10.1126/science.abk0154 Pubmed: 34762484 ]

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Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble

Release date: June 16, 2021
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7o4i
Q-score: 0.4

Schilbach S, Aibara S, Dienemann C, Grabbe F, Cramer P

Cell (2021) 184 pp. 4064-4072.e28 [ Pubmed: 34133942 DOI: doi:10.1016/j.cell.2021.05.012 ]

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Yeast RNA polymerase II transcription pre-initiation complex (consensus)

Release date: June 16, 2021
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7o4j
Q-score: 0.518

Schilbach S, Aibara S, Dienemann C, Grabbe F, Cramer P

Cell (2021) 184 pp. 4064-4072.e28 [ Pubmed: 34133942 DOI: doi:10.1016/j.cell.2021.05.012 ]

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