Electron Microscopy Data Bank

EMD-32828

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Inhibited EP-complete

Release date: Nov. 23, 2022
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 8h3u

Yang X, Ding Z, Peng L, Song Q, Zhang D, Cui F, Xia C, Li K, Yin H, Li S, Li Z, Huang H

Nat Commun (2022) 13 pp. 6955-6955 [ Pubmed: 36376282 DOI: doi:10.1038/s41467-022-34364-9 ]

Sample:

Enteropeptidase (Complex from Homo sapiens)

EMD-32714

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Structure of Active-EP

Release date: Oct. 26, 2022
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7wqw
Q-score: 0.412

Yang X, Ding Z, Peng L, Song Q, Zhang D, Cui F, Xia C, Li K, Yin H, Li S, Li Z, Huang H

Nat Commun (2022) 13 pp. 6955-6955 [ Pubmed: 36376282 DOI: doi:10.1038/s41467-022-34364-9 ]

Sample:

Enteropeptidase catalytic light chain (26 kDa, Protein from Homo sapiens)
Enteropeptidase non-catalytic heavy chain (28 kDa, Protein from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Active-ep (Complex from Homo sapiens)

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EMD-32715

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Structure of Inactive-EP

Release date: Oct. 26, 2022
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7wqx
Q-score: 0.348

Yang X, Ding Z, Peng L, Song Q, Zhang D, Cui F, Xia C, Li K, Yin H, Li S, Li Z, Huang H

Nat Commun (2022) 13 pp. 6955-6955 [ Pubmed: 36376282 DOI: doi:10.1038/s41467-022-34364-9 ]

Sample:

Enteropeptidase (55 kDa, Protein from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Inactive-ep (Complex from Homo sapiens)

EMD-32716

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Structure of Active-mutEP

Release date: Oct. 26, 2022
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7wqz
Q-score: 0.347

Yang X, Ding Z, Peng L, Song Q, Zhang D, Cui F, Xia C, Li K, Yin H, Li S, Li Z, Huang H

Nat Commun (2022) 13 pp. 6955-6955 [ Pubmed: 36376282 DOI: doi:10.1038/s41467-022-34364-9 ]

Sample:

Enteropeptidase non-catalytic heavy chain (28 kDa, Protein from Homo sapiens)
Active-mutep (Complex from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Enteropeptidase catalytic light chain (26 kDa, Protein from Homo sapiens)

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EMD-32717

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Structure of Inhibited-EP

Release date: Oct. 26, 2022
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7wr7
Q-score: 0.427

Yang X, Ding Z, Peng L, Song Q, Zhang D, Cui F, Xia C, Li K, Yin H, Li S, Li Z, Huang H

Nat Commun (2022) 13 pp. 6955-6955 [ Pubmed: 36376282 DOI: doi:10.1038/s41467-022-34364-9 ]

Sample:

Inhibited-ep (Complex from Homo sapiens)
Enteropeptidase non-catalytic heavy chain (28 kDa, Protein from Homo sapiens)
Enteropeptidase catalytic light chain (26 kDa, Protein from Homo sapiens)
4-carbamimidamidobenzoic acid (179 Da, Ligand)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)

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