Cryo-EM structure of the C1q A, B-crt, C peptide assembly narrow region
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9c9l
Q-score: 0.482
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
- Peptide from complement c1q subcomponent subunit c (1 kDa, Protein from Homo sapiens)
- Peptide from complement c1q subcomponent subunit b (1 kDa, Protein from Homo sapiens)
- Peptide from complement c1q subcomponent subunit a (1 kDa, Protein from Homo sapiens)
- Narrow region structure of the octadecameric c1q a, b-crt, c peptide assembly (70 MDa, Complex from Homo sapiens)
Cryo-EM structure of the C1q A, B-crt, C-M10F peptide assembly
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
Cryo-EM structure of the C1q A, B-crt, C peptide full assembly
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9c9u
Q-score: 0.265
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
- Complement c1q subcomponent subunit a (3 kDa, Protein from Homo sapiens)
- Complement c1q subcomponent subunit b (4 kDa, Protein from Homo sapiens)
- The c1q a, b-crt, c peptide assembly (Complex from Homo sapiens)
- Complement c1q subcomponent subunit c (3 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human C1q collagenous stem
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
Cryo-EM map of the C1q A, B-Crt, C-M10N collagenous stem assembly
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
CryoEM Structure of a FtsH Helical Assembly in the Presence of ATP
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8vw9
Q-score: 0.659
Li Y, Zhu J, Zhang Z, Wei J, Wang F, Meisl G, Knowles TPJ, Egelman EH, Tezcan FA
Nat Chem Biol (2025) [ DOI: doi:10.1038/s41589-024-01811-1 Pubmed: 39806067 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of ftsh helical assembly (Complex from Thermotoga maritima)
- Atp-dependent zinc metalloprotease ftsh (51 kDa, Protein from Thermotoga maritima)
CryoEM Structure of a FtsH Helical Assembly in the Presence of ATP
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8vwa
Q-score: 0.665
Li Y, Zhu J, Zhang Z, Wei J, Wang F, Meisl G, Knowles TPJ, Egelman EH, Tezcan FA
Nat Chem Biol (2025) [ DOI: doi:10.1038/s41589-024-01811-1 Pubmed: 39806067 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Atp-dependent zinc metalloprotease ftsh (51 kDa, Protein from Thermotoga maritima)
- Cryoem structure of ftsh helical assembly (Complex from Thermotoga maritima)
CryoEM Structure of a FtsH Helical Assembly in the Aged State
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 8vwb
Q-score: 0.649
Li Y, Zhu J, Zhang Z, Wei J, Wang F, Meisl G, Knowles TPJ, Egelman EH, Tezcan FA
Nat Chem Biol (2025) [ DOI: doi:10.1038/s41589-024-01811-1 Pubmed: 39806067 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cryoem structure of a ftsh helical assembly in the aged state (Complex from Thermotoga maritima)
- Zinc ion (65 Da, Ligand)
- Atp-dependent zinc metalloprotease ftsh (51 kDa, Protein from Thermotoga maritima)
CryoEM Structure of a FtsH Helical Assembly in the Aged State
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8vwc
Q-score: 0.664
Li Y, Zhu J, Zhang Z, Wei J, Wang F, Meisl G, Knowles TPJ, Egelman EH, Tezcan FA
Nat Chem Biol (2025) [ DOI: doi:10.1038/s41589-024-01811-1 Pubmed: 39806067 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Atp-dependent zinc metalloprotease ftsh (51 kDa, Protein from Thermotoga maritima)
- Cryo-em structure of ftsh helical assembly in the aged state (Complex from Thermotoga maritima)
Ex vivo cannulae fiber structure of Pyrodictium abyssi
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9h8b
Q-score: 0.647
Sleutel M, Sonani RR, Miller JG, Wang F, Socorro AG, Chen Y, Martin R, Demeler B, Rudolph MJ, Alva V, Remaut H, Egelman EH, Conticello VP
bioRxiv (2024) [ Pubmed: 39803462 DOI: doi:10.1101/2024.12.30.630787 ]
- Canx (18 kDa, Protein from Pyrodictium abyssi DSM 6158)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ex vivo canx fibers from pyrodictium abyssi (Complex from Pyrodictium abyssi DSM 6158)