Cryo-EM structure of the C1q A, B-crt, C peptide assembly narrow region
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9c9l
Q-score: 0.482
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
- Peptide from complement c1q subcomponent subunit c (1 kDa, Protein from Homo sapiens)
- Peptide from complement c1q subcomponent subunit b (1 kDa, Protein from Homo sapiens)
- Peptide from complement c1q subcomponent subunit a (1 kDa, Protein from Homo sapiens)
- Narrow region structure of the octadecameric c1q a, b-crt, c peptide assembly (70 MDa, Complex from Homo sapiens)
Cryo-EM structure of the C1q A, B-crt, C peptide full assembly
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 9c9u
Q-score: 0.265
Kreutzberger MAB, Yu LT, Bui TH, Hancu MC, Purdy MD, Osinski T, Kasson PM, Egelman EH, Hartgerink JD
ACS Cent Sci (2025) [ DOI: doi:10.1021/acscentsci.5c00018 ]
- Complement c1q subcomponent subunit a (3 kDa, Protein from Homo sapiens)
- Complement c1q subcomponent subunit b (4 kDa, Protein from Homo sapiens)
- The c1q a, b-crt, c peptide assembly (Complex from Homo sapiens)
- Complement c1q subcomponent subunit c (3 kDa, Protein from Homo sapiens)
Allosteric Regulation of Human Plastins
Schwebach CL, Kudryashova E, Agrawal R, Zheng W, Egelman EH, Kudryashov DS
Nat Struct Mol Biol (2022) 29 pp. 519-528 [ Pubmed: 35589838 DOI: doi:10.1038/s41594-022-00771-1 ]
Resolution: 2.46 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q5a
Q-score: 0.685
Pieri L, Wang F, Arteni AA, Vos M, Winter JM, Le Du MH, Artzner F, Gobeaux F, Legrand P, Boulard Y, Bressanelli S, Egelman EH, Paternostre M
PNAS (2022) 119 [ DOI: doi:10.1073/pnas.2120346119 Pubmed: 35042822 ]
- Lanreotide (1 MDa, Complex from Homo sapiens)
- Lanreotide (1 kDa, Protein from Homo sapiens)
Cryo-EM structure of AIM2-PYD filament
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 7k3r
Q-score: 0.488
Matyszewski M, Zheng W, Lueck J, Mazanek Z, Mohideen N, Lau AY, Egelman EH, Sohn J
Nat Commun (2021) 12 pp. 2735-2735 [ Pubmed: 33980849 DOI: doi:10.1038/s41467-021-23045-8 ]
- Interferon-inducible protein aim2 (13 kDa, Protein from Homo sapiens)
- Aim2-pyd filament (Complex from Homo sapiens)
Cryo-EM structure of F-actin/Plastin2-ABD2 complex
Resolution: 3.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 6vec
Q-score: 0.385
Schwebach CL, Kudryashova E, Zheng W, Orchard M, Smith H, Runyan LA, Egelman EH, Kudryashov DS
Bone Res (2020) 8 pp. 21-21 [ Pubmed: 32509377 DOI: doi:10.1038/s41413-020-0095-2 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Lcp1 (47 kDa, Protein from Homo sapiens)
- Plastin2-abd2 (Complex from Homo sapiens)
- F-actin (Complex from Oryctolagus cuniculus)
- Complex of plastin2-abd2 with f-actin (Complex)
Cryo-EM of peptide-like filament of 1-KMe3
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6x5i
Q-score: 0.34
Feng Z, Wang H, Wang F, Oh Y, Berciu C, Cui Q, Egelman EH, Xu B
Cell Rep Phys Sci (2020) 1 [ DOI: doi:10.1016/j.xcrp.2020.100085 Pubmed: 32776017 ]
- 1-kme3 peptide-like fibril (Complex from Homo sapiens)
- 1-kme3 peptide-like fibril (880 Da, Protein from Homo sapiens)
Cryo-EM structure of human TorsinA filament
Resolution: 4.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 6oif
Q-score: 0.221
Demircioglu FE, Zheng W, McQuown AJ, Maier NK, Watson N, Cheeseman IM, Denic V, Egelman EH, Schwartz TU
Nat Commun (2019) 10 pp. 3262-3262 [ Pubmed: 31332180 DOI: doi:10.1038/s41467-019-11194-w ]
- Torsina (Complex from Homo sapiens)
- Torsin-1a (32 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of NLRP6 PYD filament
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 6ncv
Q-score: 0.467
Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H
PNAS (2019) 116 pp. 2052-2057 [ DOI: doi:10.1073/pnas.1817221116 Pubmed: 30674671 ]
- Nacht, lrr and pyd domains-containing protein 6 (11 kDa, Protein from Homo sapiens)
- Nlrp6 pyd (Complex from Homo sapiens)
Cryo-EM structure of NLRC4-CARD filament
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 6mks
Q-score: 0.463
Matyszewski M, Zheng W, Lueck J, Antiochos B, Egelman EH, Sohn J
J Biol Chem (2018) 293 pp. 20240-20248 [ DOI: doi:10.1074/jbc.RA118.006050 Pubmed: 30385506 ]