Cryo-EM structure of a Legionella effector complexed with actin and AMP
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8jo3
Q-score: 0.618
Wang T, Song X, Tan J, Xian W, Zhou X, Yu M, Wang X, Xu Y, Wu T, Yuan K, Ran Y, Yang B, Fan G, Liu X, Zhou Y, Zhu Y
Nature (2024) 631 pp. 393-401 [ DOI: doi:10.1038/s41586-024-07573-z Pubmed: 38776962 ]
- Substrate of the dot/icm secretion system (50 kDa, Protein from Legionella sainthelensi)
- Adenosine monophosphate (347 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Cryo-em structure of a legionella effector complexed with actin and amp (Complex from Legionella sainthelensi)
Cryo-EM structure of a Legionella effector complexed with actin and ATP
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8jo4
Q-score: 0.51
Wang T, Song X, Tan J, Xian W, Zhou X, Yu M, Wang X, Xu Y, Wu T, Yuan K, Ran Y, Yang B, Fan G, Liu X, Zhou Y, Zhu Y
Nature (2024) 631 pp. 393-401 [ DOI: doi:10.1038/s41586-024-07573-z Pubmed: 38776962 ]
- Cryo-em structure of a legionella effector complexed with actin and atp (Complex from Legionella sainthelensi)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Substrate of the dot/icm secretion system (50 kDa, Protein from Legionella sainthelensi)
- Calcium ion (40 Da, Ligand)
Subnanometer in situ structure of the AcrAB-TolC efflux pump bound with MBX
Chen M, Shi X, Yu Z, Fan G, Serysheva II, Baker ML, Luisi BF, Ludtke SJ, Wang Z
Structure (2022) 30 pp. 107-113.e3 [ Pubmed: 34506732 DOI: doi:10.1016/j.str.2021.08.008 ]
- Acrab-tolc (Complex from Escherichia coli)
Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain
Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG
Nat. Struct. Mol. Biol. (2018) 26 pp. 40-49 [ DOI: 10.1038/s41594-018-0168-8 Pubmed: 30598551 ]
Image sets:
TRPV2 ion channel gating through allosteric domain coupling revealed by cryo-EM
Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG
Nat. Struct. Mol. Biol. (2018) 26 pp. 40-49 [ DOI: 10.1038/s41594-018-0168-8 Pubmed: 30598551 ]
Image sets:
Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6bo4
Q-score: 0.347
Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG
Nat Struct Mol Biol (2019) 26 pp. 40-49 [ DOI: doi:10.1038/s41594-018-0168-8 Pubmed: 30598551 ]
- Transient receptor potential cation channel subfamily v member 2 (79 kDa, Protein from Rattus norvegicus)
- Trpv2 (320 kDa, Complex from Rattus norvegicus)
TRPV2 ion channel in partially closed state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6bo5
Q-score: 0.358
Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG
Nat Struct Mol Biol (2019) 26 pp. 40-49 [ DOI: doi:10.1038/s41594-018-0168-8 Pubmed: 30598551 ]
Structure of full-length IP3R1 channel bound with Adenophostin A (composite)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6mu1
Q-score: 0.263
Fan G, Baker MR, Wang Z, Seryshev AB, Ludtke SJ, Baker ML, Serysheva II
Cell Res (2018) 28 pp. 1158-1170 [ DOI: doi:10.1038/s41422-018-0108-5 Pubmed: 30470765 ]
- Inositol 1,4,5-trisphosphate receptor type 1 (312 kDa, Protein from Rattus norvegicus)
- Adenophostin a (669 Da, Ligand)
- Inositol 1,4,5-trisphosphate receptor (1 MDa, Complex from Rattus norvegicus)
Structure of full-length IP3R1 channel in Apo-state (composite)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6mu2
Q-score: 0.31
Fan G, Baker MR, Wang Z, Seryshev AB, Ludtke SJ, Baker ML, Serysheva II
Cell Res (2018) 28 pp. 1158-1170 [ DOI: doi:10.1038/s41422-018-0108-5 Pubmed: 30470765 ]
- Inositol 1,4,5-trisphosphate receptor type 1 (313 kDa, Protein from Rattus norvegicus)
- Inositol 1,4,5-trisphosphate receptor (1 MDa, Complex from Rattus norvegicus)
Structure of full-length IP3R1 channel in ligand-bound state
Fan G, Baker MR, Wang Z, Seryshev AB, Ludtke SJ, Baker ML, Serysheva II
Cell Res (2018) 28 pp. 1158-1170 [ DOI: doi:10.1038/s41422-018-0108-5 Pubmed: 30470765 ]
- Inositol 1,4,5-trisphosphate receptor (1 MDa, Complex from Rattus norvegicus)