Resolution: 18.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8rbs
Q-score: 0.048
Homola M, Buttner CR, Fuzik T, Krepelka P, Holbova R, Novacek J, Chaillet ML, Zak J, Grybchuk D, Forster F, Wilson WH, Schroeder DC, Plevka P
Sci Adv (2024) 10 pp. eadk1954-eadk1954 [ Pubmed: 38598627 DOI: doi:10.1126/sciadv.adk1954 ]
- Major capsid protein (55 kDa, Protein from Emiliania huxleyi virus 201)
- Emiliania huxleyi virus 201 (Virus from Emiliania huxleyi virus 201)
- Penton protein (72 kDa, Protein from Emiliania huxleyi virus 201)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8rbt
Q-score: 0.097
Homola M, Buttner CR, Fuzik T, Krepelka P, Holbova R, Novacek J, Chaillet ML, Zak J, Grybchuk D, Forster F, Wilson WH, Schroeder DC, Plevka P
Sci Adv (2024) 10 pp. eadk1954-eadk1954 [ Pubmed: 38598627 DOI: doi:10.1126/sciadv.adk1954 ]
- Major capsid protein (55 kDa, Protein from Emiliania huxleyi virus 201)
- Emiliania huxleyi virus 201 (Virus from Emiliania huxleyi virus 201)
- Penton protein (72 kDa, Protein from Emiliania huxleyi virus 201)
human MutSalpha (MSH2/MSH6) binding to DNA with a GT mismatch
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ag6
Q-score: 0.542
Bruekner SR, Pieters W, Fish A, Liaci AM, Scheffers S, Rayner E, Kaldenbach D, Drost L, Dekker M, van Hees-Stuivenberg S, Delzenne-Goette E, de Konink C, Houlleberghs H, Dubbink HJ, AlSaegh A, de Wind N, Forster F, Te Riele H, Sixma TK
Nucleic Acids Res (2023) 51 pp. 1173-1188 [ Pubmed: 36715327 DOI: doi:10.1093/nar/gkad015 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mutsalpha on mismatched dna (31 kDa, Complex from Homo sapiens)
- Dna (50-mer) (15 kDa, DNA from synthetic construct)
- Dna (50-mer) (15 kDa, DNA from synthetic construct)
- Dna containing a g/t mismatch (Complex from Homo sapiens)
- Msh2 (Complex from Homo sapiens)
- Dna mismatch repair protein msh6 (158 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna mismatch repair protein msh2 (104 kDa, Protein from Homo sapiens)
- Msh6 (Complex from Homo sapiens)
Subtomogram average of the human Sec61-TRAP-OSTA-translocon
Resolution: 7.6 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8b6l
Q-score: 0.133
Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas R, Vismpas D, Grollers-Mulderij M, Koh FA, Albanese P, Scheltema RA, Howes SC, Kotecha A, Fedry J, Forster F
Nature (2023) 614 pp. 160-167 [ DOI: doi:10.1038/s41586-022-05638-5 Pubmed: 36697828 ]
- Translocon-associated protein subunit gamma (21 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit alpha isoform 1 (52 kDa, Protein from Homo sapiens)
- Signal peptide mix (1 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit (50 kDa, Protein from Homo sapiens)
- Sec61-trap-osta translocon complex (Cellular component from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (69 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit alpha (32 kDa, Protein from Homo sapiens)
- Oligosaccharyltransferase complex subunit ostc (16 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit beta (20 kDa, Protein from Homo sapiens)
- Transmembrane protein 258 (9 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 (12 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (68 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit gamma (7 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt3a (80 kDa, Protein from Homo sapiens)
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 (4 kDa, Protein from Homo sapiens)
- Protein transport protein sec61 subunit beta (9 kDa, Protein from Homo sapiens)
- Translocon-associated protein subunit delta (19 kDa, Protein from Homo sapiens)
CryoEM Structure of Extended eEF1A bound to the Ribosome in the Classical Pre State
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8b6z
Q-score: 0.306
Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas R, Vismpas D, Grollers-Mulderij M, Koh FA, Albanese P, Scheltema RA, Howes SC, Kotecha A, Fedry J, Forster F
Nature (2023) 614 pp. 160-167 [ DOI: doi:10.1038/s41586-022-05638-5 Pubmed: 36697828 ]
- Elongation factor 1-alpha 2 (50 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- Ribosome in the classical pre+ state (Complex from Homo sapiens)
Large subunit of the Chlamydomonas reinhardtii mitoribosome
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7pkt
Q-score: 0.486
Waltz F, Salinas-Giege T, Englmeier R, Meichel H, Soufari H, Kuhn L, Pfeffer S, Forster F, Engel BD, Giege P, Drouard L, Hashem Y
Nat Commun (2021) 12 pp. 7176-7176 [ Pubmed: 34887394 DOI: doi:10.1038/s41467-021-27200-z ]
- Bl32m (13 kDa, Protein from Chlamydomonas reinhardtii)
- Ml43 (16 kDa, Protein from Chlamydomonas reinhardtii)
- Unk1 (2 kDa, Protein from Chlamydomonas reinhardtii)
- Ul29m (14 kDa, Protein from Chlamydomonas reinhardtii)
- Ppr* (14 kDa, Protein from Chlamydomonas reinhardtii)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial ribosomal protein l33 (6 kDa, Protein from Chlamydomonas reinhardtii)
- Ml114 (48 kDa, Protein from Chlamydomonas reinhardtii)
- Mitochondrial ribosomal protein l17 (27 kDa, Protein from Chlamydomonas reinhardtii)
- Kow domain-containing protein,ul24m (31 kDa, Protein from Chlamydomonas reinhardtii)
- Bl27m (18 kDa, Protein from Chlamydomonas reinhardtii)
- L4 rrna (38 kDa, RNA from Chlamydomonas reinhardtii)
- Ribosomal_tl5_c domain-containing protein (38 kDa, Protein from Chlamydomonas reinhardtii)
- Ml115 (72 kDa, Protein from Chlamydomonas reinhardtii)
- Ml119 (36 kDa, Protein from Chlamydomonas reinhardtii)
- Ribosomal_l30 domain-containing protein (24 kDa, Protein from Chlamydomonas reinhardtii)
- Ml117 (75 kDa, Protein from Chlamydomonas reinhardtii)
- Mitochondrial ribosomal protein l17,bl17m (21 kDa, Protein from Chlamydomonas reinhardtii)
- Bl36m (3 kDa, Protein from Chlamydomonas reinhardtii)
- Ul4m (45 kDa, Protein from Chlamydomonas reinhardtii)
- Ul3m (44 kDa, Protein from Chlamydomonas reinhardtii)
- Ribosomal_l18e/l15p domain-containing protein (35 kDa, Protein from Chlamydomonas reinhardtii)
- Ul5m (23 kDa, Protein from Chlamydomonas reinhardtii)
- Ul22m (39 kDa, Protein from Chlamydomonas reinhardtii)
- L6 rrna (43 kDa, RNA from Chlamydomonas reinhardtii)
- Bl21m (40 kDa, Protein from Chlamydomonas reinhardtii)
- 50s ribosomal protein l9, chloroplastic (30 kDa, Protein from Chlamydomonas reinhardtii)
- Mitochondrial ribosomal protein l23 (25 kDa, Protein from Chlamydomonas reinhardtii)
- Ribosomal_l2_c domain-containing protein (41 kDa, Protein from Chlamydomonas reinhardtii)
- Ml80 (27 kDa, Protein from Chlamydomonas reinhardtii)
- L3b rrna (59 kDa, RNA from Chlamydomonas reinhardtii)
- Unk2 (4 kDa, Protein from Chlamydomonas reinhardtii)
- Mitochondrial ribosomal protein l13 (29 kDa, Protein from Chlamydomonas reinhardtii)
- Ml41 (12 kDa, Protein from Chlamydomonas reinhardtii)
- L5 rrna (47 kDa, RNA from Chlamydomonas reinhardtii)
- Bl28m (17 kDa, Protein from Chlamydomonas reinhardtii)
- Bl35m (17 kDa, Protein from Chlamydomonas reinhardtii)
- L2a rrna (27 kDa, RNA from Chlamydomonas reinhardtii)
- Plastid ribosomal protein l6 (22 kDa, Protein from Chlamydomonas reinhardtii)
- Mitochondrial ribosomal protein l19 (33 kDa, Protein from Chlamydomonas reinhardtii)
- L1 rrna (51 kDa, RNA from Chlamydomonas reinhardtii)
- Magnesium ion (24 Da, Ligand)
- Ml113 (84 kDa, Protein from Chlamydomonas reinhardtii)
- Ml40 (17 kDa, Protein from Chlamydomonas reinhardtii)
- Zinc ion (65 Da, Ligand)
- Bl34m (29 kDa, Protein from Chlamydomonas reinhardtii)
- L7 rrna (186 kDa, RNA from Chlamydomonas reinhardtii)
- Ul14m (13 kDa, Protein from Chlamydomonas reinhardtii)
- Ml59/64 (14 kDa, Protein from Chlamydomonas reinhardtii)
- 50s ribosomal protein l20 (13 kDa, Protein from Chlamydomonas reinhardtii)
- Ml116 (53 kDa, Protein from Chlamydomonas reinhardtii)
- Ml118 (64 kDa, Protein from Chlamydomonas reinhardtii)
- Large subunit of the mitochondrial ribosome of chlamydomonas reinhardtii (Complex from Chlamydomonas reinhardtii)
- L8 rrna (132 kDa, RNA from Chlamydomonas reinhardtii)
- Ml87 (23 kDa, Protein from Chlamydomonas reinhardtii)
- Ribosomal_l16 domain-containing protein (27 kDa, Protein from Chlamydomonas reinhardtii)
- Ml63/57/60 (14 kDa, Protein from Chlamydomonas reinhardtii)
- L3a rrna (5s) (24 kDa, RNA from Chlamydomonas reinhardtii)
Human Signal Peptidase Complex Paralog A (SPC-A)
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 7p2p
Q-score: 0.232
Liaci AM, Steigenberger B, Telles de Souza PC, Tamara S, Grollers-Mulderij M, Ogrissek P, Marrink SJ, Scheltema RA, Forster F
Mol Cell (2021) 81 pp. 3934-3948.e11 [ DOI: doi:10.1016/j.molcel.2021.07.031 Pubmed: 34388369 ]
- Signal peptidase complex subunit 3 (spc22/23) (Complex from Homo sapiens)
- Signal peptidase complex subunit 1 (spc12) (Complex from Homo sapiens)
- Signal peptidase complex paralog a (spc-a) (20 kDa, Complex from Homo sapiens)
- Signal peptidase complex subunit 1 (20 kDa, Protein from Homo sapiens)
- Signal peptidase complex catalytic subunit a (sec11a) (Complex from Homo sapiens)
- Signal peptidase complex subunit 3 (22 kDa, Protein from Homo sapiens)
- Signal peptidase complex subunit 2 (spc25) (Complex from Homo sapiens)
- Signal peptidase complex catalytic subunit sec11a (22 kDa, Protein from Homo sapiens)
- Signal peptidase complex subunit 2 (27 kDa, Protein from Homo sapiens)
Human Signal Peptidase Complex Paralog C (SPC-C)
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 7p2q
Q-score: 0.237
Liaci AM, Steigenberger B, Telles de Souza PC, Tamara S, Grollers-Mulderij M, Ogrissek P, Marrink SJ, Scheltema RA, Forster F
Mol Cell (2021) 81 pp. 3934-3948.e11 [ DOI: doi:10.1016/j.molcel.2021.07.031 Pubmed: 34388369 ]
- Signal peptidase complex subunit 3 (spc22/23) (Complex from Homo sapiens)
- Signal peptidase complex catalytic subunit c (sec11c) (Complex from Homo sapiens)
- Signal peptidase complex subunit 1 (spc12) (Complex from Homo sapiens)
- Signal peptidase complex subunit 1 (20 kDa, Protein from Homo sapiens)
- Signal peptidase complex subunit 3 (22 kDa, Protein from Homo sapiens)
- Signal peptidase complex subunit 2 (spc25) (Complex from Homo sapiens)
- Signal peptidase complex subunit 2 (27 kDa, Protein from Homo sapiens)
- Signal peptidase complex catalytic subunit sec11c (23 kDa, Protein from Homo sapiens)
- Signal peptidase complex paralog c (spc-c) (20 kDa, Complex from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7akd
Q-score: 0.413
Fedry J, Hurdiss DL, Wang C, Li W, Obal G, Drulyte I, Du W, Howes SC, van Kuppeveld FJM, Forster F, Bosch BJ
Sci Adv (2021) 7 [ Pubmed: 33958322 DOI: doi:10.1126/sciadv.abf5632 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of the sars-cov-2 spike glycoprotein with the 47d11 neutralizing antibody fab fragment (550 kDa, Complex from Homo sapiens)
- Alpha-l-fucopyranose (164 Da, Ligand)
- 47d11 neutralizing antibody light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 47d11 neutralizing antibody heavy chain (13 kDa, Protein from Homo sapiens)
- Alpha-d-mannopyranose (180 Da, Ligand)
Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6xiq
Q-score: 0.33
Zhou Y, Kastritis PL, Dougherty SE, Bouvette J, Hsu AL, Burbaum L, Mosalaganti S, Pfeffer S, Hagen WJH, Forster F, Borgnia MJ, Vogel C, Beck M, Bartesaghi A, Silva GM
PNAS (2020) 117 pp. 22157-22166 [ Pubmed: 32855298 DOI: doi:10.1073/pnas.2005301117 ]
- 60s ribosomal protein l19-a (21 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s10-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l7-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Rpl8a isoform 1 (28 kDa, Protein from Saccharomyces cerevisiae)
- K63 ubiquitinated ribosome (3 MDa, Complex from Saccharomyces cerevisiae)
- 40s ribosomal protein s16-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l43-a (10 kDa, Protein from Saccharomyces cerevisiae)
- Rpl32 isoform 1 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l14-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s6-a (27 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l31-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l36-a (11 kDa, Protein from Saccharomyces cerevisiae)
- Rpl29 isoform 1 (6 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Rpl12a isoform 1 (17 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s21-a (9 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s11-a (17 kDa, Protein from Saccharomyces cerevisiae)
- Rpl9a isoform 1 (21 kDa, Protein from Saccharomyces cerevisiae)
- Rps3 isoform 1 (26 kDa, Protein from Saccharomyces cerevisiae)
- Rps20 isoform 1 (13 kDa, Protein from Saccharomyces cerevisiae)
- Rps29a isoform 1 (6 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l35-a (13 kDa, Protein from Saccharomyces cerevisiae)
- Rps26b isoform 1 (13 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l30 (11 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l23-a (14 kDa, Protein from Saccharomyces cerevisiae)
- Rps25a isoform 1 (12 kDa, Protein from Saccharomyces cerevisiae)
- Rps5p (25 kDa, Protein from Saccharomyces cerevisiae)
- Rps22a isoform 1 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l6-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l2-a (27 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Rpl38 isoform 1 (8 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l40 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l25 (15 kDa, Protein from Saccharomyces cerevisiae)
- 5s ribosomal rna (38 kDa, RNA from Saccharomyces cerevisiae)
- Rps15 isoform 1 (16 kDa, Protein from Saccharomyces cerevisiae)
- Rpl11b isoform 1 (19 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l15-a (24 kDa, Protein from Saccharomyces cerevisiae)
- Mrna (2 kDa, RNA from Saccharomyces cerevisiae)
- Rpl24a isoform 1 (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l20-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l33-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l42-a (12 kDa, Protein from Saccharomyces cerevisiae)
- Rps2 isoform 1 (27 kDa, Protein from Saccharomyces cerevisiae)
- Rpl4a isoform 1 (39 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-b (14 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s9-a (22 kDa, Protein from Saccharomyces cerevisiae)
- Rpl10 isoform 1 (25 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l18-a (20 kDa, Protein from Saccharomyces cerevisiae)
- Transfer rna (24 kDa, RNA from Saccharomyces cerevisiae)
- 60s ribosomal protein l34-a (13 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l28 (16 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l21-a (18 kDa, Protein from Saccharomyces cerevisiae)
- Rpl3 isoform 1 (43 kDa, Protein from Saccharomyces cerevisiae)
- 35s ribosomal rna (1 MDa, RNA from Saccharomyces cerevisiae)
- 5.8s ribosomal rna (50 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s0-a (28 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s17-b (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s23-a (16 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l13-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l17-a (20 kDa, Protein from Saccharomyces cerevisiae)
- Rps8a isoform 1 (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l16-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s19-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l39 (6 kDa, Protein from Saccharomyces cerevisiae)
- Rpl5 isoform 1 (33 kDa, Protein from Saccharomyces cerevisiae)
- Rpp0 isoform 1 (33 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s30-a (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s18-a (17 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s4-a (29 kDa, Protein from Saccharomyces cerevisiae)
- Rpl41a isoform 1 (3 kDa, Protein from Saccharomyces cerevisiae)
- Rpl1a isoform 1 (24 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l27-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Rps1a isoform 1 (28 kDa, Protein from Saccharomyces cerevisiae)
- Rps28a isoform 1 (7 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l37-a (9 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s13 (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l26-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 18s ribosomal rna (579 kDa, RNA from Saccharomyces cerevisiae)
- 60s ribosomal protein l22-a (13 kDa, Protein from Saccharomyces cerevisiae)