Cryo-EM structure of human HCN3 channel with cAMP
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8io0
Q-score: 0.42
Cryo-EM structure of human HCN3 channel in apo state
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8inz
Q-score: 0.526
Yu B, Lu Q, Li J, Cheng X, Hu H, Li Y, Che T, Hua Y, Jiang H, Zhang Y, Xian C, Yang T, Fu Y, Chen Y, Nan W, McCormick PJ, Xiong B, Duan J, Zeng B, Li Y, Fu Y, Zhang J
J Biol Chem (2024) 300 pp. 107288-107288 [ Pubmed: 38636662 DOI: doi:10.1016/j.jbc.2024.107288 ]
- 4-[[(2~{s},4~{a}~{r},6~{s},8~{a}~{s})-6-[(4~{s},5~{r})-4-[(2~{s})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{h}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid (492 Da, Ligand)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (86 kDa, Protein from Homo sapiens)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Complex from Homo sapiens)
Cryo-EM structure of CopC-CaM-caspase-3 with NAD+
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 7xn4
Q-score: 0.492
Zhang K, Peng T, Tao X, Tian M, Li Y, Wang Z, Ma S, Hu S, Pan X, Xue J, Luo J, Wu Q, Fu Y, Li S
Mol Cell (2022) 82 pp. 4712-4726.e7 [ DOI: doi:10.1016/j.molcel.2022.10.032 Pubmed: 36423631 ]
- Arginine adp-riboxanase copc (52 kDa, Protein from Chromobacterium violaceum)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- Cryo-em structure of copc-cam-caspase-3 with nad+ (Complex from Homo sapiens)
- Caspase-3 (31 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Cryo-EM structure of CopC-CaM-caspase-3 with ADPR
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 7xn5
Q-score: 0.517
Zhang K, Peng T, Tao X, Tian M, Li Y, Wang Z, Ma S, Hu S, Pan X, Xue J, Luo J, Wu Q, Fu Y, Li S
Mol Cell (2022) 82 pp. 4712-4726.e7 [ DOI: doi:10.1016/j.molcel.2022.10.032 Pubmed: 36423631 ]
- Arginine adp-riboxanase copc (52 kDa, Protein from Chromobacterium violaceum)
- Nicotinamide (122 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Caspase-3 (31 kDa, Protein from Homo sapiens)
- Cryo-em structure of copc-cam-caspase-3 with adpr (Complex from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Cryo-EM structure of CopC-CaM-caspase-3 with ADPR-deacylization
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 7xn6
Q-score: 0.466
Zhang K, Peng T, Tao X, Tian M, Li Y, Wang Z, Ma S, Hu S, Pan X, Xue J, Luo J, Wu Q, Fu Y, Li S
Mol Cell (2022) 82 pp. 4712-4726.e7 [ DOI: doi:10.1016/j.molcel.2022.10.032 Pubmed: 36423631 ]
- Arginine adp-riboxanase copc (52 kDa, Protein from Chromobacterium violaceum)
- Nicotinamide (122 Da, Ligand)
- Caspase-3 (32 kDa, Protein from Homo sapiens)
- Cryo-em structure of copc-cam-caspase-3 with adpr-deacylization (Complex from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
CryoEM structure of full length mouse TRPML2
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 7dys
Q-score: 0.438
Song X, Li J, Tian M, Zhu H, Hu X, Zhang Y, Cao Y, Ye H, McCormick PJ, Zeng B, Fu Y, Duan J, Zhang J
J Biol Chem (2022) 298 pp. 101487-101487 [ DOI: doi:10.1016/j.jbc.2021.101487 Pubmed: 34915027 ]
- Mucolipin-2 (60 kDa, Protein from Mus musculus)
- Trpml2 (Cellular component from Mus musculus)