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author:"Fu Y" AND citation_journal_name:"TO BE PUBLISHED" AND author_name:"Kim"
Cryo-EM Structure of Mouse TLR4/MD-2/DLAM3 Complex
Release date: Oct. 23, 2024
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8wry
Q-score: 0.533
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8wry
Q-score: 0.533
To Be Published
Sample:
- 2-(hydroxymethyl)-5-methoxy-3,6-bis(oxidanyl)pyran-4-one (188 Da, Ligand)
- (3r)-3-(tetradecanoyloxy)tetradecanoic acid (454 Da, Ligand)
- Lymphocyte antigen 96 (16 kDa, Protein from Mus musculus)
- Mouse tlr4/md2/dlam3 complex (Complex from Mus musculus)
- (3r)-3-(dodecanoyloxy)tetradecanoic acid (426 Da, Ligand)
- 2-amino-2-deoxy-4-o-phosphono-alpha-d-glucopyranose (259 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toll-like receptor 4 (68 kDa, Protein from Mus musculus)
Cryo-EM Structure of Mouse TLR4/MD-2/DLAM5 Complex
Release date: Oct. 23, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wsa
Q-score: 0.475
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wsa
Q-score: 0.475
To Be Published
Sample:
- (3~{s})-3-decanoyloxytetradecanoic acid (398 Da, Ligand)
- Mouse tlr4/md2/dlam5 complex (Complex from Mus musculus)
- (3r)-3-(tetradecanoyloxy)tetradecanoic acid (454 Da, Ligand)
- Lymphocyte antigen 96 (16 kDa, Protein from Mus musculus)
- [(2~{r},3~{s},4~{r},5~{s})-2-(hydroxymethyl)-5-methoxy-4,6-bis(oxidanyl)oxan-3-yl] dihydrogen phosphate (274 Da, Ligand)
- (3r)-3-(dodecanoyloxy)tetradecanoic acid (426 Da, Ligand)
- 2-amino-2-deoxy-4-o-phosphono-alpha-d-glucopyranose (259 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toll-like receptor 4 (68 kDa, Protein from Mus musculus)
Cryo-EM Structure of Human TLR4/MD-2/DLAM3 Complex
Release date: Oct. 23, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wta
Q-score: 0.474
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wta
Q-score: 0.474
To Be Published
Sample:
- Toll-like receptor 4 (68 kDa, Protein from Homo sapiens)
- 2-(hydroxymethyl)-5-methoxy-3,6-bis(oxidanyl)pyran-4-one (188 Da, Ligand)
- Human tlr4/md2/dlam3 complex (Complex from Homo sapiens)
- Lymphocyte antigen 96 (16 kDa, Protein from Homo sapiens)
- (3r)-3-(tetradecanoyloxy)tetradecanoic acid (454 Da, Ligand)
- (3r)-3-(dodecanoyloxy)tetradecanoic acid (426 Da, Ligand)
- 2-amino-2-deoxy-4-o-phosphono-alpha-d-glucopyranose (259 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM Structure of Mouse TLR4/MD-2/DLAM1 complex
Release date: Oct. 16, 2024
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8wqt
Q-score: 0.375
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8wqt
Q-score: 0.375
To Be Published
Sample:
- Mouse tlr4/md2/dlam1 complex (Complex from Mus musculus)
- (3r)-3-(tetradecanoyloxy)tetradecanoic acid (454 Da, Ligand)
- [(2~{r},3~{s},4~{s},5~{s})-5-methoxy-3,4,6-tris(oxidanyl)oxan-2-yl]methyl dihydrogen phosphate (274 Da, Ligand)
- Lymphocyte antigen 96 (16 kDa, Protein from Mus musculus)
- (3r)-3-(dodecanoyloxy)tetradecanoic acid (426 Da, Ligand)
- 2-amino-2-deoxy-4-o-phosphono-alpha-d-glucopyranose (259 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toll-like receptor 4 (68 kDa, Protein from Mus musculus)
Cryo-EM Structure of Human TLR4/MD-2/DLAM5 Complex
Release date: Oct. 9, 2024
Resolution: 2.24 Å
EM Method: Single-particle
Fitted PDBs: 8wo1
Q-score: 0.587
Resolution: 2.24 Å
EM Method: Single-particle
Fitted PDBs: 8wo1
Q-score: 0.587
To Be Published
Sample:
- (3~{s})-3-decanoyloxytetradecanoic acid (398 Da, Ligand)
- Toll-like receptor 4 (68 kDa, Protein from Homo sapiens)
- Lymphocyte antigen 96 (16 kDa, Protein from Homo sapiens)
- Human tlr4/md2/dlam5 complex (Complex from Homo sapiens)
- (3r)-3-(tetradecanoyloxy)tetradecanoic acid (454 Da, Ligand)
- [(2~{r},3~{s},4~{r},5~{s})-2-(hydroxymethyl)-5-methoxy-4,6-bis(oxidanyl)oxan-3-yl] dihydrogen phosphate (274 Da, Ligand)
- (3r)-3-(dodecanoyloxy)tetradecanoic acid (426 Da, Ligand)
- 2-amino-2-deoxy-4-o-phosphono-alpha-d-glucopyranose (259 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)