Complex of FMDV O/18074 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8y0q
Q-score: 0.621
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Complex of fmdv o/18074 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
- Vp3 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus O)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus O)
- Fmdv o/18074 (Complex from Foot-and-mouth disease virus O)
- Poa2 vh (13 kDa, Protein from Sus scrofa)
Complex of FMDV A/WH/CHA/09 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8y0r
Q-score: 0.578
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Complex of fmdv a/wh/cha/09 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Vp3 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Fmdv a/wh/cha/09 (Complex from Foot-and-mouth disease virus A)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus A)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus A)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Poa2 vh (13 kDa, Protein from Sus scrofa)
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8jkd
Q-score: 0.612
CCHFV envelope protein Gc in complex with Gc8
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlw
Q-score: 0.513
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Mouse antibody gc8 light chain (11 kDa, Protein from Mus musculus)
- Cchfv envelope protein gc-gc8 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
- Mouse antibody gc8 heavy chain (12 kDa, Protein from Mus musculus)
- Glycoprotein c,cchfv envelope protein gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
CCHFV envelope protein Gc in complex with Gc13
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlx
Q-score: 0.51
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Mouse antibody gc13 light chain (11 kDa, Protein from Mus musculus)
- Cchfv envelope protein gc-gc13 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
- Glycoprotein c,cchfv gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
- Mouse antibody gc13 heavy chain (12 kDa, Protein from Mus musculus)
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (global refinement)
Changrob S, Halfmann PJ, Liu H, Torres JL, McGrath JJC, Ozorowski G, Li L, Wilbanks GD, Kuroda M, Maemura T, Huang M, Zheng NY, Turner HL, Erickson SA, Fu Y, Yasuhara A, Singh G, Monahan B, Mauldin J, Srivastava K, Simon V, Krammer F, Sather DN, Ward AB, Wilson IA, Kawaoka Y, Wilson PC
J Clin Inv (2023) 133 [ Pubmed: 36862518 DOI: doi:10.1172/JCI166844 ]
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8d0z
Q-score: 0.42
Changrob S, Halfmann PJ, Liu H, Torres JL, McGrath JJC, Ozorowski G, Li L, Wilbanks GD, Kuroda M, Maemura T, Huang M, Zheng NY, Turner HL, Erickson SA, Fu Y, Yasuhara A, Singh G, Monahan B, Mauldin J, Srivastava K, Simon V, Krammer F, Sather DN, Ward AB, Wilson IA, Kawaoka Y, Wilson PC
J Clin Inv (2023) 133 [ Pubmed: 36862518 DOI: doi:10.1172/JCI166844 ]
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S728-1157 fab heavy chain variable region (12 kDa, Protein from Homo sapiens)
- S728-1157 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- S728-1157 igg in complex with sars-cov-2-6p-mut7 s protein (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of a class T GPCR in apo state
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7xp4
Q-score: 0.428
Xu W, Wu L, Liu S, Liu X, Cao X, Zhou C, Zhang J, Fu Y, Guo Y, Wu Y, Tan Q, Wang L, Liu J, Jiang L, Fan Z, Pei Y, Yu J, Cheng J, Zhao S, Hao X, Liu ZJ, Hua T
Science (2022) 377 pp. 1298-1304 [ Pubmed: 36108005 DOI: doi:10.1126/science.abo1633 ]
- Guanine nucleotide-binding protein g(t) subunit alpha-3 (30 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Complex of gpcr and g protein (Complex from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Endoglucanase h,taste receptor type 2 member 46,endoglucanase h,taste receptor type 2 member 46,bitter taste receptor t2r46 (91 kDa, Protein from Homo sapiens)
Cryo-EM structure of a class T GPCR in ligand-free state
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7xp5
Q-score: 0.412
Xu W, Wu L, Liu S, Liu X, Cao X, Zhou C, Zhang J, Fu Y, Guo Y, Wu Y, Tan Q, Wang L, Liu J, Jiang L, Fan Z, Pei Y, Yu J, Cheng J, Zhao S, Hao X, Liu ZJ, Hua T
Science (2022) 377 pp. 1298-1304 [ Pubmed: 36108005 DOI: doi:10.1126/science.abo1633 ]
- Guanine nucleotide-binding protein g(t) subunit alpha-3 (30 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Endoglucanase h,taste receptor type 2 member 46,bitter taste receptor t2r46 (91 kDa, Protein from Homo sapiens)
- Complex of gpcr and g protein (Complex from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Cryo-EM structure of a class T GPCR in active state
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7xp6
Q-score: 0.415
Xu W, Wu L, Liu S, Liu X, Cao X, Zhou C, Zhang J, Fu Y, Guo Y, Wu Y, Tan Q, Wang L, Liu J, Jiang L, Fan Z, Pei Y, Yu J, Cheng J, Zhao S, Hao X, Liu ZJ, Hua T
Science (2022) 377 pp. 1298-1304 [ Pubmed: 36108005 DOI: doi:10.1126/science.abo1633 ]
- Strychnine (334 Da, Ligand)
- Guanine nucleotide-binding protein g(t) subunit alpha-3 (30 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Complex of gpcr and g protein (Complex from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Endoglucanase h,taste receptor type 2 member 46,endoglucanase h,taste receptor type 2 member 46,bitter taste receptor t2r46 (91 kDa, Protein from Homo sapiens)