CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 8p7b
Q-score: 0.615
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Magnesium ion (24 Da, Ligand)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Mettl6 trna serrs complex in a 1:2:2 stoichiometry (Complex from Homo sapiens)
CryoEM structure of METTL6 tRNA SerRS complex in a 2:2:2 stoichiometry
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8p7c
Q-score: 0.268
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Mettl6 trna serrs complex in a 2:2:2 stoichiometry (Complex from Homo sapiens)
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
CryoEM structure of METTL6 tRNA SerRS complex in a 1:1:2 stoichiometry
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8p7d
Q-score: 0.271
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serine--trna ligase, cytoplasmic (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Serine trna (27 kDa, RNA from Trichoplusia ni)
- Trna n(3)-methylcytidine methyltransferase mettl6 (33 kDa, Protein from Homo sapiens)
- Mettl6 trna serrs complex in a 1:1:2 stoichiometry (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]
- Serrs homodimer (Protein from Homo sapiens)
- Mettl6 trna serrs complex in a 1:2:2 stoichiometry (Complex)
- Serine trna (RNA from Trichoplusia ni)
- Sers (Complex from Homo sapiens)
- Trna (Complex from Trichoplusia ni)
Serine tRNA from Trichoplusia ni
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo L, Basu S, Kaiser S, Schneider R, Kowalinski E
Nat Struct Mol Biol (2024) 31 pp. 1614-1624 [ DOI: doi:10.1038/s41594-024-01341-3 Pubmed: 38918637 ]