Structure of 1:1 PAPP-A.ProMBP complex(half map)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 7y5n
Q-score: 0.476
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pappalysin-1 (172 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Structure of 1:1 papp-a/prombp complex(half map) (Complex from Homo sapiens)
- Bone marrow proteoglycan (25 kDa, Protein from Homo sapiens)
Structure of 1:1 PAPP-A.STC2 complex(half map)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7y5q
Q-score: 0.438
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Maltose/maltodextrin-binding periplasmic protein,pappalysin-1 (216 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Structure of 1:1 papp-a/stc2 complex(half map) (Complex from Homo sapiens)
- Stanniocalcin-2 (33 kDa, Protein from Homo sapiens)
Structure of 2:2 PAPP-A.ProMBP comple
Resolution: 3.64 Å
EM Method: Single-particle
Fitted PDBs: 8hgg
Q-score: 0.408
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Bone marrow proteoglycan (25 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Structure of 2:2 papp-a/prombp complex (Complex from Homo sapiens)
- Pappalysin-1 (181 kDa, Protein from Homo sapiens)
Structure of 2:2 PAPP-A.STC2 complex
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 8hgh
Q-score: 0.295
Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J
Cell Discov (2022) 8 pp. 137-137 [ Pubmed: 36550107 DOI: doi:10.1038/s41421-022-00502-2 ]
- Structure of 2:2 papp-a/stc2 complex (Complex from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,pappalysin-1 (216 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Stanniocalcin-2 (33 kDa, Protein from Homo sapiens)
Architecture of mammalian respirasome
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 5gpn
Q-score: 0.143
Gu J, Wu M, Guo R, Yan K, Lei J, Gao N, Yang M
Nature (2016) 537 pp. 639-643 [ DOI: doi:10.1038/nature19359 Pubmed: 27654917 ]
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8 (23 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (7 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 9 (7 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (1 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6a2, mitochondrial (9 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 7b, mitochondrial (6 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (6 kDa, Protein from Bos taurus)
- Heme c (618 Da, Ligand)
- Cytochrome c1, heme protein, mitochondrial (27 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2 (52 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5 (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Bos taurus)
- Cytochrome b-c1 complex subunit 1, mitochondrial (49 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 7c, mitochondrial (5 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (3 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 5a, mitochondrial (12 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 8b, mitochondrial (4 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3 (30 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (2 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Bos taurus)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (16 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1 (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (13 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (17 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (1 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Bos taurus)
- Cytochrome c oxidase subunit 5b, mitochondrial (10 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (11 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (46 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Cytochrome b-c1 complex subunit 6, mitochondrial (9 kDa, Protein from Bos taurus)
- Mitochondrial nadh dehydrogenase fe-s protein 4 (19 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (79 kDa, Protein from Sus scrofa)
- Acyl carrier protein (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Bos taurus)
- Respirasome (1 MDa, Complex from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 unknown subunit fragment (6 kDa, Protein from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Bos taurus)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7 (23 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from Sus scrofa)
Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 5h4p
Q-score: 0.483
State 1 of cryo-EM structure of the yeast pre-60S particles isolated with Nog2-TAP
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 3jct
Q-score: 0.468
Wu S, Tutunchuoglu B, Yan K, Brown H, Zhang YX, Tan D, Gamalinda M, Yuan Y, Li ZF, Jakovljevic J, Ma CY, Lei JL, Dong M-Q, Woolford J, Gao N
Nature (2016) 534 pp. 133-137 [ DOI: doi:10.1038/nature17942 Pubmed: 27251291 ]
State 2 of cryo-EM structure of the yeast pre-60S particles isolated with Nog2-TAP
Wu S, Tutunchuoglu B, Yan K, Brown H, Zhang YX, Tan D, Gamalinda M, Yuan Y, Li ZF, Jakovljevic J, Ma CY, Lei JL, Dong M-Q, Woolford J, Gao N
Nature (2016) 534 pp. 133-137 [ DOI: doi:10.1038/nature17942 Pubmed: 27251291 ]
Cryo-EM structures of the 50S ribosome subunit bound with HflX
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 5ady
Q-score: 0.289
Zhang Y, Mandava CS, Cao W, Li X, Zhang D, Li N, Zhang Y, Zhang X, Qin Y, Mi K, Lei J, Sanyal S, Gao N
Nat Struct Mol Biol (2015) 22 pp. 906-913 [ Pubmed: 26458047 DOI: doi:10.1038/nsmb.3103 ]
- Prokaryotic 50s ribosome subunit (1 MDa, Complex from Escherichia coli K-12)
- 50s-hflx complex (1 MDa, Sample)
- Hflx (50 kDa, Protein from Escherichia coli)