Cryo-EM structure of the human CTP synthase filament
Resolution: 6.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 5u03
Q-score: 0.177
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
- Ctp synthase 1 (66 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Human ctp synthase 1 filament (Complex from Homo sapiens)
- Uridine 5'-triphosphate (484 Da, Ligand)
Cryo-EM structure of the E. coli CTP synthase tetramer
Resolution: 7.9 Å
EM Method: Single-particle
Fitted PDBs: 5u05
Q-score: 0.132
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
- E. coli ctp synthase tetramer (Complex from Escherichia coli)
- Ctp synthase (60 kDa, Protein from Escherichia coli)
human CTP synthase 1 - mutant H355A
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
- Hctps1-h355a tetramer (Complex from Homo sapiens)
- Hctps1-h355a (Protein from Homo sapiens)
E. coli CTP synthase CC mutant filament
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
E. coli CTP synthase CC mutant filament
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution
Resolution: 4.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 5u3c
Q-score: 0.259
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Ctp synthase filament (Complex from Escherichia coli)
- Cytidine-5'-triphosphate (483 Da, Ligand)
- Ctp synthase (60 kDa, Protein from Escherichia coli)
E. coli CTP synthase CC mutant filament (product-bound)
Resolution: 5.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 5u6r
Q-score: 0.177
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM
Nat Struct Mol Biol (2017) 24 pp. 507-514 [ DOI: doi:10.1038/nsmb.3407 Pubmed: 28459447 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- E. coli ctp synthase cc mutant filament (Complex from Escherichia coli)
- Cytidine-5'-triphosphate (483 Da, Ligand)
- Ctp synthase (60 kDa, Protein from Escherichia coli)
Cryo-EM structure of the CTP synthetase filament
Barry RM, Bitbol A-F, Lorestani A, Charles EJ, Habrian CH, Hansen JM, Li H-J, Baldwin EP, Wingreen NS, Kollman JM, Gitai Z
eLife (2014) 3 pp. e03638-e03638 [ Pubmed: 25030911 DOI: doi:10.7554/eLife.03638 ]
- Ctp synthetase (56 kDa, Protein from Escherichia coli)
- Ctp synthetase filament (Sample)