Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
bioRxiv (2022) [ Pubmed: 35118469 DOI: doi:10.1101/2022.01.25.477784 ]
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 7tge
Q-score: 0.342
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tl1
Q-score: 0.441
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7tl9
Q-score: 0.411
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7tei
Q-score: 0.464
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7tf8
Q-score: 0.468
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 7the
Q-score: 0.414
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
- Rbd directed antibody dh1042 in complex with sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Dh1042 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Dh1042 fab light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
CryoEM map of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042
Resolution: 3.42 Å
EM Method: Single-particle
Fitted PDBs: 7tht
Q-score: 0.407
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
- Dh1042 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dh1042 light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with rbd antibody dh1042 (Complex)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody dh1042 (Complex from Homo sapiens)
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7tou
Q-score: 0.466
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta (b.1.617.2) sars-cov-2 variant spike protein (s-gsas-delta) in the 3-rbd-down conformation; consensus state, d1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 7tov
Q-score: 0.484
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
Mol Cell (2022) 82 pp. 2050-2068.e6 [ DOI: doi:10.1016/j.molcel.2022.03.028 Pubmed: 35447081 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Delta (b.1.617.2) sars-cov-2 variant spike protein (s-gsas-delta) in the 1-rbd-up conformation; consensus state, d2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)