Zebrafish MFSD2A isoform B in inward open ligand bound conformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8d2s
Q-score: 0.543
Nguyen C, Lei HT, Lai LTF, Gallenito MJ, Mu X, Matthies D, Gonen T
Nat Commun (2023) 14 pp. 2571-2571 [ Pubmed: 37156797 DOI: doi:10.1038/s41467-023-37702-7 ]
- Water (18 Da, Ligand)
- Single-particle cryo-em map of mfsd2a isoform b from zebrafish with a fab in the inward open ligand bound conformation at an average resolution of 2.9 a, filtered to local resolution (56 kDa, Complex from Danio rerio)
- Fab heavy chain (20 kDa, Protein from Mus musculus)
- [(2~{r})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] (9~{z},12~{z},15~{z})-octadeca-9,12,15-trienoate (518 Da, Ligand)
- Sodium-dependent lysophosphatidylcholine symporter 1-b (56 kDa, Protein from Danio rerio)
- Fab light chain (20 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Zebrafish MFSD2A isoform B in inward open ligand-free conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8d2t
Q-score: 0.481
Nguyen C, Lei HT, Lai LTF, Gallenito MJ, Mu X, Matthies D, Gonen T
Nat Commun (2023) 14 pp. 2571-2571 [ Pubmed: 37156797 DOI: doi:10.1038/s41467-023-37702-7 ]
- Water (18 Da, Ligand)
- Fab heavy chain (20 kDa, Protein from Mus musculus)
- Sodium-dependent lysophosphatidylcholine symporter 1-b (56 kDa, Protein from Danio rerio)
- Fab light chain (20 kDa, Protein from Mus musculus)
- Single-particle cryo-em map of mfsd2a isoform b from zebrafish with a fab in the inward open ligand-free conformation at an average resolution of 3.4 a, filtered to local resolution (56 kDa, Complex from Danio rerio)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
Zebrafish MFSD2A isoform B in inward open ligand 1A conformation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8d2u
Q-score: 0.489
Nguyen C, Lei HT, Lai LTF, Gallenito MJ, Mu X, Matthies D, Gonen T
Nat Commun (2023) 14 pp. 2571-2571 [ Pubmed: 37156797 DOI: doi:10.1038/s41467-023-37702-7 ]
- Water (18 Da, Ligand)
- Fab heavy chain (20 kDa, Protein from Mus musculus)
- [(2~{r})-2-oxidanyl-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] (9~{z},12~{z},15~{z})-octadeca-9,12,15-trienoate (518 Da, Ligand)
- Sodium-dependent lysophosphatidylcholine symporter 1-b (56 kDa, Protein from Danio rerio)
- Single-particle cryo-em map of mfsd2a isoform b from zebrafish with a fab in the inward open ligand 1a conformation at an average resolution of 3.3 a, filtered to local resolution (56 kDa, Complex from Danio rerio)
- Fab light chain (20 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)