Cryo-EM structure of human GPR156-Gi3 complex
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8yk0
Q-score: 0.501
Ma X, Chen LN, Liao M, Zhang L, Xi K, Guo J, Shen C, Shen DD, Cai P, Shen Q, Qi J, Zhang H, Zang SK, Dong YJ, Miao L, Qin J, Ji SY, Li Y, Liu J, Mao C, Zhang Y, Chai R
Nat Commun (2024) 15 pp. 10601-10601 [ Pubmed: 39638804 DOI: doi:10.1038/s41467-024-54681-5 ]
- Probable g-protein coupled receptor 156 (35 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Bos taurus)
- (21r,24r,27s)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9z)-octadec-9-enoate (777 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-3 (40 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 156 (32 kDa, Protein from Homo sapiens)
- Gpr156-gi3 complex (Cellular component from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xx4
Q-score: 0.605
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Rna polymerase subunit 6 (12 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*cp*gp*cp*ap*ap*cp*gp*gp*cp*gp*a)-3') (3 kDa, DNA from African swine fever virus)
- Asfv rnap elongation complex (Complex from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*tp*tp*cp*gp*cp*cp*gp*tp*tp*gp*cp*gp*tp*ap*tp*tp*tp*gp*tp*gp*tp*ap*g)-3') (7 kDa, DNA from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Magnesium ion (24 Da, Ligand)
- Rna (5'-r(p*cp*up*ap*cp*ap*cp*ap*ap*a)-3') (2 kDa, RNA from African swine fever virus)
- D339l (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (138 kDa, Protein from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex1 (MCOC1)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8xx5
Q-score: 0.607
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- D339l (38 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex1 (mcoc1) (Complex from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- M1249l (137 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xxp
Q-score: 0.591
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- C147l (11 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- D339l (16 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Asfv rnap core complex (Complex from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex2 (MCOC2)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8xxt
Q-score: 0.525
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- D339l (38 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- M1249l (135 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex2 (mcoc2) (Complex from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9bjo
Q-score: 0.605
Guo J, Zia A, Qiu Q, Norton M, Qiu K, Usuba J, Liu Z, Yi M, Rich-New ST, Hagan M, Fraden S, Han GD, Diao J, Wang F, Xu B
J Am Chem Soc (2024) 146 pp. 26102-26112 [ Pubmed: 39255453 DOI: doi:10.1021/jacs.4c06775 ]
- Ffsy fiber (Complex from synthetic construct)
- D-peptide ffsy (770 Da, Protein from synthetic construct)
The early intermediate structure of baculovirus fusion protein GP64
Cryo-EM structure of the MM07-bound human APLNR-Gi complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xzh
Q-score: 0.649
Wang WW, Ji SY, Zhang W, Zhang J, Cai C, Hu R, Zang SK, Miao L, Xu H, Chen LN, Yang Z, Guo J, Qin J, Shen DD, Liang P, Zhang Y, Zhang Y
Cell (2024) 187 pp. 1460-1475.e20 [ DOI: doi:10.1016/j.cell.2024.02.004 Pubmed: 38428423 ]
- Apelin receptor (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Mm07 (1 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cryo-em structure of the mm07-bound human aplnr-gi complex (Complex from Homo sapiens)
- Scfv16 (27 kDa, Protein from synthetic construct)
Cryo-EM structure of the CMF-019-bound human APLNR-Gi complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8xzi
Q-score: 0.588
Wang WW, Ji SY, Zhang W, Zhang J, Cai C, Hu R, Zang SK, Miao L, Xu H, Chen LN, Yang Z, Guo J, Qin J, Shen DD, Liang P, Zhang Y, Zhang Y
Cell (2024) 187 pp. 1460-1475.e20 [ DOI: doi:10.1016/j.cell.2024.02.004 Pubmed: 38428423 ]
- Apelin receptor (42 kDa, Protein from Homo sapiens)
- (3~{s})-5-methyl-3-[[1-pentan-3-yl-2-(thiophen-2-ylmethyl)benzimidazol-5-yl]carbonylamino]hexanoic acid (455 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cryo-em structure of the cmf-019-bound human aplnr-gi complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)