HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch
Resolution: 2.12 Å
EM Method: Single-particle
Fitted PDBs: 9enp
Q-score: 0.588
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Dna (Complex from synthetic construct)
- Dna polymerase-processivity factor (Complex from Human alphaherpesvirus 1 strain KOS)
- Water (18 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Dna (46-mer) (13 kDa, DNA from synthetic construct)
- Dna (67-mer) (20 kDa, DNA from synthetic construct)
- Hsv-1 dna polymerase-processivity factor complex in exonuclease state with 1-bp dna mismatch (Complex)
- Dna polymerase processivity factor (51 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Calcium ion (40 Da, Ligand)
Resolution: 2.12 Å
EM Method: Single-particle
Fitted PDBs: 9enq
Q-score: 0.677
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Dna polymerase-processivity factor (Complex from Human alphaherpesvirus 1 strain KOS)
- Water (18 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Dna (46-mer) (13 kDa, DNA from synthetic construct)
- Dna (67-mer) (20 kDa, DNA from synthetic construct)
- Hsv-1 dna polymerase-processivity factor complex in exonuclease state with 1-bp dna mismatch (Complex)
- Dna (Complex from synthetic construct)
- Calcium ion (40 Da, Ligand)
HSV-1 DNA polymerase-processivity factor complex in pre-translocation state
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 8oj6
Q-score: 0.555
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Magnesium ion (24 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Hsv-1 dna polymerase-processivity factor complex in pre-translocation state (Complex from Human alphaherpesvirus 1 strain KOS)
- Water (18 Da, Ligand)
- Dna (48-mer) (14 kDa, DNA from synthetic construct)
- Dna polymerase processivity factor (51 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Dna (22-mer) (6 kDa, DNA from synthetic construct)
HSV-1 DNA polymerase-processivity factor complex in halted elongation state
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8oj7
Q-score: 0.583
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Magnesium ion (24 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Dna (53-mer) (16 kDa, DNA from synthetic construct)
- 2'-deoxyadenosine 5'-triphosphate (491 Da, Ligand)
- Hsv-1 dna polymerase-processivity factor complex in halted elongation state (Complex from Human alphaherpesvirus 1 strain KOS)
- Dna (67-mer) (20 kDa, DNA from synthetic construct)
- Dna polymerase processivity factor (51 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
HSV-1 DNA polymerase-processivity factor complex in exonuclease state
Resolution: 1.87 Å
EM Method: Single-particle
Fitted PDBs: 8oja
Q-score: 0.684
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Water (18 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Calcium ion (40 Da, Ligand)
- Hsv-1 dna polymerase-processivity factor complex in exonuclease state (Complex from Human alphaherpesvirus 1 strain KOS)
- Dna (68-mer) (21 kDa, DNA from synthetic construct)
- Dna polymerase processivity factor (51 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Dna (47-mer) (14 kDa, DNA from synthetic construct)
HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site
Resolution: 1.9 Å
EM Method: Single-particle
Fitted PDBs: 8ojb
Q-score: 0.723
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Water (18 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Calcium ion (40 Da, Ligand)
- Hsv-1 dna polymerase-processivity factor complex in exonuclease state (Complex from Human alphaherpesvirus 1 strain KOS)
- Dna (47-mer) (14 kDa, DNA from synthetic construct)
HSV-1 DNA polymerase active site in alternative exonuclease state
Resolution: 2.08 Å
EM Method: Single-particle
Fitted PDBs: 8ojc
Q-score: 0.673
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Water (18 Da, Ligand)
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Calcium ion (40 Da, Ligand)
- Hsv-1 dna polymerase-processivity factor complex in exonuclease state (Complex from Human alphaherpesvirus 1 strain KOS)
- Dna (47-mer) (14 kDa, DNA from synthetic construct)
HSV-1 DNA polymerase beta-hairpin loop
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8ojd
Q-score: 0.534
Gustavsson E, Grunewald K, Elias P, Hallberg BM
Nucleic Acids Res (2024) 52 pp. 7292-7304 [ DOI: doi:10.1093/nar/gkae374 Pubmed: 38806233 ]
- Dna polymerase catalytic subunit (136 kDa, Protein from Human alphaherpesvirus 1 strain KOS)
- Hsv-1 dna polymerase focused on beta-hairpin loop (Complex from Human alphaherpesvirus 1 strain KOS)
- Dna (68-mer) (21 kDa, DNA from synthetic construct)
- Calcium ion (40 Da, Ligand)
- Dna (47-mer) (14 kDa, DNA from synthetic construct)