Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8sbb
Q-score: 0.46
Guo X, Zhang J, Han L, Lee J, Williams SC, Forsberg A, Xu Y, Austin RN, Feng L
Nat Commun (2023) 14 pp. 2180-2180 [ Pubmed: 37069165 DOI: doi:10.1038/s41467-023-37869-z ]
- Nanobody (14 kDa, Protein from synthetic construct)
- Alkane 1-monooxygenase (45 kDa, Protein from Fontimonas thermophila)
- Ftaklb-nanobody (Complex from Fontimonas thermophila)
- Fe (iii) ion (55 Da, Ligand)
- Dodecane (170 Da, Ligand)
Resolution: 7.4 Å
EM Method: Single-particle
Fitted PDBs: 7q3n
Q-score: 0.069
Stsiapanava A, Xu C, Nishio S, Han L, Yamakawa N, Carroni M, Tunyasuvunakool K, Jumper J, de Sanctis D, Wu B, Jovine L
Nat Struct Mol Biol (2022) 29 pp. 190-193 [ Pubmed: 35273390 DOI: doi:10.1038/s41594-022-00729-3 ]
- Uromodulin (Complex from Homo sapiens)
- Type 1 fimbiral adhesin fimh (18 kDa, Protein from Escherichia coli (strain UTI89 / UPEC))
- Complex of human uromodulin (umod)/tamm-horsfall protein (thp) and the lectin domain of the fimh adhesin of uropathogenic e. coli (Complex)
- Uromodulin (61 kDa, Protein from Homo sapiens)
- Type 1 fimbiral adhesin fimh (Complex from Escherichia coli (strain UTI89 / UPEC))
CryoEM structure of SGLT1 at 3.4 A resolution
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7sl8
Q-score: 0.467
Han L, Qu Q, Aydin D, Panova O, Robertson MJ, Xu Y, Dror RO, Skiniotis G, Feng L
Nature (2022) 601 pp. 274-279 [ Pubmed: 34880492 DOI: doi:10.1038/s41586-021-04211-w ]
- Nanobody-sglt complex (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Nanobody nb1 (14 kDa, Protein from synthetic construct)
- Sodium/glucose cotransporter 1 (74 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7sl9
Q-score: 0.463
Han L, Qu Q, Aydin D, Panova O, Robertson MJ, Xu Y, Dror RO, Skiniotis G, Feng L
Nature (2022) 601 pp. 274-279 [ Pubmed: 34880492 DOI: doi:10.1038/s41586-021-04211-w ]
- Sodium-coupled monocarboxylate transporter 1 (67 kDa, Protein from Homo sapiens)
- Butanoic acid (88 Da, Ligand)
- Nanobody nb2 (14 kDa, Protein from synthetic construct)
- Smct1 and nanobody complex (Complex from Homo sapiens)
CryoEM structure of SGLT1 at 3.15 angstrom resolution
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7sla
Q-score: 0.505
Han L, Qu Q, Aydin D, Panova O, Robertson MJ, Xu Y, Dror RO, Skiniotis G, Feng L
Nature (2022) 601 pp. 274-279 [ Pubmed: 34880492 DOI: doi:10.1038/s41586-021-04211-w ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- Nanobody nb1 (14 kDa, Protein from synthetic construct)
- Sglt1 and nanobody complex (Complex from Homo sapiens)
- Sodium/glucose cotransporter 1 (74 kDa, Protein from Homo sapiens)