Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rr1
Q-score: 0.512
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
- 3-hydroxyacyl-coa dehydrogenase type-2a (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Trna methyltransferase 10 homolog c (Complex from Homo sapiens)
- Trna methyltransferase 10 homolog c (37 kDa, Protein from Homo sapiens)
- Zinc phosphodiesterase elac protein 2 (Complex from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc phosphodiesterase elac protein 2 (89 kDa, Protein from Homo sapiens)
- Human mitochondrial rnase z complex with trna-tyr precursor (Complex)
- Human mitochondrial trna-tyr precursor with 3' trailer (29 kDa, RNA from Homo sapiens)
- Trna-tyr precursor (Complex from Homo sapiens)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
Consensus map of human mitochondrial RNase Z complex with ELAC2-D550N mutant and tRNA-Gln precursor
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rr3
Q-score: 0.415
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
- Zinc ion (65 Da, Ligand)
- Trna methyltransferase 10 homolog c (37 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc phosphodiesterase elac protein 2 (89 kDa, Protein from Homo sapiens)
- Human mitochondrial trna-gln precursor with 3' trailer rna (31 kDa, RNA from Homo sapiens)
- Human mitochondrial rnase z complex with trna-gln precursor (Complex from Homo sapiens)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
Consensus refinement map of human mitochondrial RNase Z complex with tRNA-Gln precursor
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8rr4
Q-score: 0.464
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
- Human mitochondria trna-tyr precursor with 3' trailer (29 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Trna methyltransferase 10 homolog c (37 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Human mitochondrial rnase z complex with trna-tyr precursor (Complex from Homo sapiens)
- Zinc phosphodiesterase elac protein 2 (89 kDa, Protein from Homo sapiens)
- 3-hydroxyacyl-coa dehydrogenase type-2 (26 kDa, Protein from Homo sapiens)
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Human mitochondrial RNase Z complex with tRNA-Tyr precursor - Focused map around ELAC2
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Human mitochondrial RNase Z complex with tRNA-Gln precursor - Focused map around ELAC2
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen HS
Nat Struct Mol Biol (2025) [ DOI: doi:10.1038/s41594-024-01445-w Pubmed: 39747487 ]
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7b3b
Q-score: 0.501
Kokic G, Hillen HS, Tegunov D, Dienemann C, Seitz F, Schmitzova J, Farnung L, Siewert A, Hobartner C, Cramer P
Nat Commun (2021) 12 pp. 279-279 [ Pubmed: 33436624 DOI: doi:10.1038/s41467-020-20542-0 ]
- Sars-cov-2 rna-dependent rna polymerase complex (nsp12, nsp7, nsp8) with elongation scaffold containing remdesivir at position -3. (Complex)
- Sars-cov-2 rna-dependent rna polymerase (nsp12) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna-directed rna polymerase nsp12 (107 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Dna/rna (5'-r(p*cp*up*ap*cp*gp*cp*g)-d(p*(rmp))-r(p*up*g)-3') (4 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(p*up*gp*cp*ap*up*cp*gp*cp*gp*up*ap*g)-3') (18 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Dna and rna (Complex from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 nsp7 and nsp8 (Complex from Severe acute respiratory syndrome coronavirus 2)