structure of a membrane-integrated glycosyltransferase with inhibitor
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xs6
Q-score: 0.572
Wu Y, Zhang M, Yang Y, Ding X, Yang P, Huang K, Hu X, Zhang M, Liu X, Yu H
Cell Discov (2022) 8 pp. 129-129 [ DOI: doi:10.1038/s41421-022-00495-y Pubmed: 36473834 ]
- Tetradecane (198 Da, Ligand)
- Membrane-integrated glycosyltransferase (Complex from Saccharomyces cerevisiae)
- Chitin synthase 1 (130 kDa, Protein from Saccharomyces cerevisiae)
- (2s)-{[(2s,3s,4s)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name) (495 Da, Ligand)
- Heptane (100 Da, Ligand)
- (19r,22s)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9z)-hexadec-9-enoate (689 Da, Ligand)
- Dodecane (170 Da, Ligand)
structure of a membrane-integrated glycosyltransferase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7xs7
Q-score: 0.547
Wu Y, Zhang M, Yang Y, Ding X, Yang P, Huang K, Hu X, Zhang M, Liu X, Yu H
Cell Discov (2022) 8 pp. 129-129 [ DOI: doi:10.1038/s41421-022-00495-y Pubmed: 36473834 ]
- Tetradecane (198 Da, Ligand)
- Membrane-integrated glycosyltransferase (Complex from Saccharomyces cerevisiae)
- Chitin synthase 1 (130 kDa, Protein from Saccharomyces cerevisiae)
- Heptane (100 Da, Ligand)
- (19r,22s)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9z)-hexadec-9-enoate (689 Da, Ligand)
- Dodecane (170 Da, Ligand)
structure of a membrane-bound glycosyltransferase
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xe4
Q-score: 0.471
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from Saccharomyces cerevisiae)
- Tetradecane (198 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
- Decane (142 Da, Ligand)
- Nonane (128 Da, Ligand)
- Heptane (100 Da, Ligand)
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Dodecane (170 Da, Ligand)
Structure of a mutated membrane-bound glycosyltransferase
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yuy
Q-score: 0.494
Hu X, Yang P, Chai C, Liu J, Sun H, Wu Y, Zhang M, Zhang M, Liu X, Yu H
Nature (2023) 616 pp. 190-198 [ Pubmed: 36949198 DOI: doi:10.1038/s41586-023-05856-5 ]
- Tetradecane (198 Da, Ligand)
- (11r,14s)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate (495 Da, Ligand)
- 1,3-beta-glucan synthase component fks1 (215 kDa, Protein from Saccharomyces cerevisiae)
- Decane (142 Da, Ligand)
- Nonane (128 Da, Ligand)
- Heptane (100 Da, Ligand)
- Membrane-bound glycosyltransferase (215 kDa, Complex from Saccharomyces cerevisiae)
- Dodecane (170 Da, Ligand)
SARS-CoV-2 S trimer in complex with 1F Fab
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7y7j
Q-score: 0.383
Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G
Protein Cell (2023) 14 pp. 74-78 [ Pubmed: 36726762 DOI: doi:10.1093/procel/pwac042 ]
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike glycoprotein complex with 1f fab (Complex)
- 1f fab (Complex from Homo sapiens)
- 1f vh (14 kDa, Protein from Homo sapiens)
- 1f vl (11 kDa, Protein from Homo sapiens)
SARS-CoV-2 RBD in complex with 1F Fab
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7y7k
Q-score: 0.241
Zhao S, Liu F, Qiu S, Lan Q, Wu Y, Xu W, Ke J, Yang J, Liu X, Wang K, Guo H, Xia S, Zhang F, Wang J, Hu X, Lu L, Jiang S, Zhao S, Liu L, Xie Y, Yang X, Wang H, Zhong G
Protein Cell (2023) 14 pp. 74-78 [ Pubmed: 36726762 DOI: doi:10.1093/procel/pwac042 ]
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 rbd complex with 1f fab (Complex)
- 1f fab (Complex from Homo sapiens)
- 1f vh (14 kDa, Protein from Homo sapiens)
- Spike protein s1 (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 1f vl (11 kDa, Protein from Homo sapiens)