GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of LBD-TMD-TARPgamma2
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 9b5z
Q-score: 0.53
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of TMD-TARPgamma2
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 9b60
Q-score: 0.553
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH5, consensus structure of LBD-TMD-TARPgamma2
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 9b61
Q-score: 0.428
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH5, consensus structure of TMD-TARPgamma2
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 9b63
Q-score: 0.507
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH5, class23, structure of LBD-TMD-TARPgamma2
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 9b64
Q-score: 0.431
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH8, class1, structure of LBD-TMD-TARPgamma2
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 9b67
Q-score: 0.51
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
GluA2 flip Q in complex with TARPgamma2 at pH8, class1, structure of NTD
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9b68
Q-score: 0.458
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
- Glua2 (flip-q isoform) (Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Tarpgamma2 (Complex from Mus musculus)
- Glua2 (flip-q isoform) in complex with tarpgamma2 at 4:4 stoichiometry (500 kDa, Complex)
- Isoform flip of glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of NTD
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 9b69
Q-score: 0.464
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
- Glua2 (flip-q isoform) (Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Tarpgamma2 (Complex from Mus musculus)
- Glua2 (flip-q isoform) in complex with tarpgamma2 at 4:4 stoichiometry (500 kDa, Complex)
- Isoform flip of glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of LBD-TMD-TARPgamma2
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 9b6a
Q-score: 0.488
Ivica J, Kejzar N, Ho H, Stockwell I, Kuchtiak V, Scrutton AM, Nakagawa T, Greger IH
Nat Struct Mol Biol (2024) 31 pp. 1601-1613 [ DOI: doi:10.1038/s41594-024-01369-5 Pubmed: 39138332 ]
Active state homomeric GluA1 AMPA receptor in complex with TARP gamma 3
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8c1p
Q-score: 0.561
Zhang D, Ivica J, Krieger JM, Ho H, Yamashita K, Stockwell I, Baradaran R, Cais O, Greger IH
Nature (2023) 621 pp. 877-882 [ Pubmed: 37704721 DOI: doi:10.1038/s41586-023-06528-0 ]
- Palmitic acid (256 Da, Ligand)
- Glutamate receptor 1 flip isoform (102 kDa, Protein from Rattus norvegicus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Cyclothiazide (389 Da, Ligand)
- (2r)-2,3-dihydroxypropyl (9z)-octadec-9-enoate (356 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Homomeric glua1 ampa receptor in complex with tarp gamma 3 (Complex from Rattus)
- Water (18 Da, Ligand)
- Voltage-dependent calcium channel gamma-3 subunit (35 kDa, Protein from Rattus norvegicus)