Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ifg
Q-score: 0.441
Wang X, Wang Y, Liu S, Zhang Y, Xu K, Ji L, Kornberg RD, Zhang H
PNAS (2023) 120 pp. e2307598120- [ DOI: doi:10.1073/pnas.2307598120 Pubmed: 37459529 ]
- Chromatin modification-related protein eaf3 (39 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Water (18 Da, Ligand)
- Cph2 (68 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Cryo-em structure of the clr6-hdac (clr6s) complex from s. pombe (600 kDa, Complex from Schizosaccharomyces pombe)
- Zinc ion (65 Da, Ligand)
- Rbap48-related wd40 repeat-containing protein prw1 (48 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Paired amphipathic helix protein pst2 (125 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Histone deacetylase clr6 (45 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Cph1 (45 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
Clr6 HDAC (Clr6S)-nucleosome complex
Wang X, Wang Y, Liu S, Zhang Y, Xu K, Ji L, Kornberg RD, Zhang H
PNAS (2023) 120 pp. e2307598120-e2307598120 [ DOI: doi:10.1073/pnas.2307598120 Pubmed: 37459529 ]
Rpd3S-nucleosome (H3K36me3 modified)
Wang X, Wang Y, Liu S, Zhang Y, Xu K, Ji L, Kornberg RD, Zhang H
PNAS (2023) 120 pp. e2307598120-e2307598120 [ DOI: doi:10.1073/pnas.2307598120 Pubmed: 37459529 ]
The NuA4 histone acetyltransferase complex from S. cerevisiae
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7yfp
Q-score: 0.334
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ DOI: doi:10.1073/pnas.2214313119 Pubmed: 36417436 ]
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- The nua4 histone acetyltransferase complex (Complex from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
Core module of the NuA4 complex in S. cerevisiae
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yfn
Q-score: 0.414
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ DOI: doi:10.1073/pnas.2214313119 Pubmed: 36417436 ]
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- Cryo-em structure of nua4 complex (Complex from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)