Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8ifg
Q-score: 0.441
Wang X, Wang Y, Liu S, Zhang Y, Xu K, Ji L, Kornberg RD, Zhang H
PNAS (2023) 120 pp. e2307598120- [ DOI: doi:10.1073/pnas.2307598120 Pubmed: 37459529 ]
- Chromatin modification-related protein eaf3 (39 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Water (18 Da, Ligand)
- Cph2 (68 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Cryo-em structure of the clr6-hdac (clr6s) complex from s. pombe (600 kDa, Complex from Schizosaccharomyces pombe)
- Zinc ion (65 Da, Ligand)
- Rbap48-related wd40 repeat-containing protein prw1 (48 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Paired amphipathic helix protein pst2 (125 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Histone deacetylase clr6 (45 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
- Cph1 (45 kDa, Protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843))
Resolution: 3.75 Å
EM Method: Single-particle
Fitted PDBs: 8ouw
Q-score: 0.329
Xia Y, Sonneville R, Jenkyn-Bedford M, Ji L, Alabert C, Hong Y, Yeeles JTP, Labib KPM
Science (2023) 381 pp. eadi4932-eadi4932 [ DOI: doi:10.1126/science.adi4932 Pubmed: 37590372 ]
- Dna replication licensing factor mcm-5 (85 kDa, Protein from Caenorhabditis elegans)
- Dna replication complex gins protein psf3 (21 kDa, Protein from Caenorhabditis elegans)
- Cell division control protein 45 homolog (66 kDa, Protein from Caenorhabditis elegans)
- Dna replication licensing factor mcm2 (99 kDa, Protein from Caenorhabditis elegans)
- Dna replication licensing factor mcm-4 (91 kDa, Protein from Caenorhabditis elegans)
- Dna replication licensing factor mcm7 (81 kDa, Protein from Caenorhabditis elegans)
- Complex of cmg helicase bound to tim-1/tipn-1 and homodimeric dnsn-1 on fork dna (caenorhabditis elegans) (Complex from Caenorhabditis elegans)
- Magnesium ion (24 Da, Ligand)
- Dna leading strand template (26 kDa, DNA from Saccharomyces cerevisiae)
- Downstream neighbor of son homolog (66 kDa, Protein from Caenorhabditis elegans)
- Probable dna replication complex gins protein psf2 (20 kDa, Protein from Caenorhabditis elegans)
- Dna replication licensing factor mcm3 (90 kDa, Protein from Caenorhabditis elegans)
- Protein tipin homolog (27 kDa, Protein from Caenorhabditis elegans)
- Zinc ion (65 Da, Ligand)
- Dna replication licensing factor mcm-6 (91 kDa, Protein from Caenorhabditis elegans)
- Probable dna replication complex gins protein psf1 (23 kDa, Protein from Caenorhabditis elegans)
- Dna replication complex gins protein sld5 (25 kDa, Protein from Caenorhabditis elegans)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Dna lagging strand template (18 kDa, DNA from Saccharomyces cerevisiae)
- Protein timeless homolog (157 kDa, Protein from Caenorhabditis elegans)
Cannabinoid Receptor 1-G Protein Complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ghv
Q-score: 0.569
Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B
Nat Commun (2023) 14 pp. 2672-2672 [ DOI: doi:10.1038/s41467-023-37864-4 Pubmed: 37160876 ]
- Cannabinoid receptor 1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cannabinoid receptor 1 in complex with gi protein heterotrimer and scfv16 (Complex from Homo sapiens)
- (5z,8z,11z,13s,14z)-n-[(2r)-1-hydroxypropan-2-yl]-13-methylicosa-5,8,11,14-tetraenamide (375 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Scfv16 (Complex from Mus musculus)
- Cannabinoid receptor 1 (55 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gi g protein heterotrimer (Complex from Homo sapiens)
The NuA4 histone acetyltransferase complex from S. cerevisiae
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7yfp
Q-score: 0.334
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ DOI: doi:10.1073/pnas.2214313119 Pubmed: 36417436 ]
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- The nua4 histone acetyltransferase complex (Complex from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
Core module of the NuA4 complex in S. cerevisiae
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yfn
Q-score: 0.414
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H
PNAS (2022) 119 pp. e2214313119-e2214313119 [ DOI: doi:10.1073/pnas.2214313119 Pubmed: 36417436 ]
- Enhancer of polycomb-like protein 1 (96 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Swr1-complex protein 4 (55 kDa, Protein from Saccharomyces cerevisiae)
- Cryo-em structure of nua4 complex (Complex from Saccharomyces cerevisiae)
- Transcription-associated protein 1 (433 kDa, Protein from Saccharomyces cerevisiae)
- Arp4 isoform 1 (54 kDa, Protein from Saccharomyces cerevisiae)
- Actin (41 kDa, Protein from Saccharomyces cerevisiae)
- Chromatin modification-related protein eaf1 (112 kDa, Protein from Saccharomyces cerevisiae)