Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 6xsk
Q-score: 0.406
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M
Immunity (2022) 55 pp. 2405-2418.e7 [ DOI: doi:10.1016/j.immuni.2022.10.015 Pubmed: 36356572 ]
- 789-203-3c12 fab heavy and light chains (Cellular component from Macaca mulatta)
- 789-203-3c12 fab heavy chain (49 kDa, Protein from Macaca mulatta)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- 789-203-3c12 fab light chain (23 kDa, Protein from Macaca mulatta)
- Influenza hemagglutinin (Cellular component from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Influenza hemagglutinin si06 trimer in complex with 789-203-3c12 fab (Cellular component)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 6zxn
Q-score: 0.468
Hanke L, Vidakovics Perez L, Sheward DJ, Das H, Schulte T, Moliner-Morro A, Corcoran M, Achour A, Karlsson Hedestam GB, Hallberg BM, Murrell B, McInerney GM
Nat Commun (2020) 11 pp. 4420-4420 [ Pubmed: 32887876 DOI: doi:10.1038/s41467-020-18174-5 ]
- Nanobody ty1 (Complex from Vicugna pacos)
- Nanobody ty1 (14 kDa, Protein from Vicugna pacos)
- Ternary complex between nanobody ty1 and spike. (14 kDa, Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nanobody strongly neutralising and blocks ace2 binding. (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6ot1
Q-score: 0.429
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- 0pv-b.01 light (23 kDa, Protein from Macaca mulatta)
- 0pv-b.01 (Complex from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 light (22 kDa, Protein from Homo sapiens)
- Vrc03 light (23 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- Bg505 gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 heavy (25 kDa, Protein from Homo sapiens)
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-b.01, vrc03 and pgt122 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 (Complex from Homo sapiens)
- Vrc03 heavy (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- 0pv-b.01 heavy (24 kDa, Protein from Macaca mulatta)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6mph
Q-score: 0.404
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Df1w-a.01 (Complex from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Df1w-a.01 heavy chain (12 kDa, Protein from Macaca mulatta)
- Df1w-a.01 light chain (12 kDa, Protein from Macaca mulatta)
- Pgt122 (Complex from Homo sapiens)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Df1w-a.01 fab bound to hiv-1 env bg505 ds-sosip-vrc03 fab- pgt122 fab (630 kDa, Complex)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6n1v
Q-score: 0.373
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- A12v163-a.01 (Complex from Macaca mulatta)
- Quaternary complex of hiv-1 env bg505 ds-sosip with antibodies 17d4, vrc03 and pgt122. (630 kDa, Complex)
- A12v163-a.01 light chain (22 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgt122 (Complex from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp4 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- A12v163-a.01 heavy chain (23 kDa, Protein from Macaca mulatta)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Vrc03 (Complex from Homo sapiens)
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (14 kDa, Protein from Homo sapiens)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6n1w
Q-score: 0.314
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Vrc03 light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Dfph-a.15 (Complex from Macaca mulatta)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Quaternary complex of hiv-1 env bg505 ds-sosip with antibodies dfph-a.15, vrc03 and pgt122. (630 kDa, Complex)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 (Complex from Homo sapiens)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Dfph-a.15 light chain (22 kDa, Protein from Macaca mulatta)
- Vrc03 heavy chain (14 kDa, Protein from Homo sapiens)
- Dfph-a.15 heavy chain (24 kDa, Protein from Macaca mulatta)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6nf2
Q-score: 0.405
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-c.01, vrc03 and pgt122 (Complex)
- 0pv-c.01 light chain (23 kDa, Protein from Homo sapiens)
- 0pv-c.01 (Complex from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc03 light chain (23 kDa, Protein from Homo sapiens)
- Vrc03 heavy chain (25 kDa, Protein from Homo sapiens)
- Pgt122 light chain (22 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- 0pv-c.01 heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgt122 heavy chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- Vrc03 (Complex from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6osy
Q-score: 0.396
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, Shen CH, Zhang B, Zhou T, Chuang GY, Chao CW, Gu Y, Jafari AJ, Louder MK, O'Dell S, Rowshan AP, Viox EG, Wang Y, Choi CW, Corcoran MM, Corrigan AR, Dandey VP, Eng ET, Geng H, Foulds KE, Guo Y, Kwon YD, Lin B, Liu K, Mason RD, Nason MC, Ohr TY, Ou L, Rawi R, Sarfo EK, Schon A, Todd JP, Wang S, Wei H, Wu W, Mullikin JC, Bailer RT, Doria-Rose NA, Karlsson Hedestam GB, Scorpio DG, Overbaugh J, Bloom JD, Carragher B, Potter CS, Shapiro L, Kwong PD, Mascola JR
Cell (2019) 178 pp. 567-584.e19 [ Pubmed: 31348886 DOI: doi:10.1016/j.cell.2019.06.030 ]
- Vrc03 light (23 kDa, Protein from Homo sapiens)
- Pgt122 heavy (25 kDa, Protein from Homo sapiens)
- Pgt122 (Complex from Homo sapiens)
- Hiv-1 env bg505 ds-sosip and antibodies 0pv-a.01, vrc03 and pgt122 (Complex)
- Bg505 gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- 0pv-a.01 heavy (25 kDa, Protein from Homo sapiens)
- 0pv-a.01 light (23 kDa, Protein from Homo sapiens)
- 0pv-a.01 (Complex from Homo sapiens)
- Vrc03 heavy (25 kDa, Protein from Homo sapiens)
- Bg505 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vrc03 (Complex from Homo sapiens)
- Pgt122 light (22 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (Complex from Human immunodeficiency virus 1)