Structure of Ran bound to RCC1 and the nucleosome core particle (composite map)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ux1
Q-score: 0.609
Huang SK, Rubinstein JL, Kay LE
To Be Published
- 153-bp widom 601 dna forward strand (47 kDa, DNA from synthetic construct)
- Regulator of chromosome condensation (44 kDa, Protein from Homo sapiens)
- Histone h2b (13 kDa, Protein from Drosophila melanogaster)
- Histone h3 (15 kDa, Protein from Drosophila melanogaster)
- 153-bp widom 601 dna reverse strand (46 kDa, DNA from synthetic construct)
- Histone h2a (13 kDa, Protein from Drosophila melanogaster)
- Histone h4 (11 kDa, Protein from Drosophila melanogaster)
- Ran-rcc1-ncp complex (Complex from Homo sapiens)
- Gtp-binding nuclear protein ran (24 kDa, Protein from Homo sapiens)
Cryo-EM maps of the NCP-RCC1-Ran complex with multiple binding states
Focused-refinement map of the RCC1-Ran region from the NCP-RCC1-Ran complex
ClpP from Neisseria meningitidis - Compressed conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7kr2
Q-score: 0.474
NmClpP compressed conformation
Ripstein ZA, Vahidi S, Rubinstein JL, Kay LE
J Am Chem Soc (2020) 142 pp. 20519-20523 [ Pubmed: 33232135 DOI: doi:10.1021/jacs.0c09474 ]
- Caseinolytic protease (316 kDa, Complex from Neisseria meningitidis)
ClpP1P2 complex from M. tuberculosis
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6vgk
Q-score: 0.491
Vahidi S, Ripstein ZA, Juravsky JB, Rennella E, Goldberg AL, Mittermaier AK, Rubinstein JL, Kay LE
PNAS (2020) 117 pp. 5895-5906 [ Pubmed: 32123115 DOI: doi:10.1073/pnas.1921630117 ]
- Atp-dependent clp protease proteolytic subunit 1 (21 kDa, Protein from Mycobacterium tuberculosis)
- Clpp1p2 complex (300 kDa, Complex from Mycobacterium tuberculosis)
- Atp-dependent clp protease proteolytic subunit 2 (21 kDa, Protein from Mycobacterium tuberculosis)
ClpP1P2 complex from M. tuberculosis bound to ADEP
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6vgn
Q-score: 0.494
Vahidi S, Ripstein ZA, Juravsky JB, Rennella E, Goldberg AL, Mittermaier AK, Rubinstein JL, Kay LE
PNAS (2020) 117 pp. 5895-5906 [ Pubmed: 32123115 DOI: doi:10.1073/pnas.1921630117 ]
- Atp-dependent clp protease proteolytic subunit 1 (21 kDa, Protein from Mycobacterium tuberculosis)
- R0m-wfp-alo-pro-ycp-ala-mp8 (800 Da, Protein from synthetic construct)
- Clpp1p2 complex with adep (300 kDa, Complex from Mycobacterium tuberculosis)
- Atp-dependent clp protease proteolytic subunit (21 kDa, Protein from Mycobacterium tuberculosis)
ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6vgq
Q-score: 0.459
Vahidi S, Ripstein ZA, Juravsky JB, Rennella E, Goldberg AL, Mittermaier AK, Rubinstein JL, Kay LE
PNAS (2020) 117 pp. 5895-5906 [ Pubmed: 32123115 DOI: doi:10.1073/pnas.1921630117 ]
- Clpp1p2 complex bound to glf-cmk (300 kDa, Complex from Mycobacterium tuberculosis)
- Atp-dependent clp protease proteolytic subunit 1 (21 kDa, Protein from Mycobacterium tuberculosis)
- Z-gly-leu-phe-ch2cl (520 Da, Protein from synthetic construct)
- Atp-dependent clp protease proteolytic subunit (21 kDa, Protein from Mycobacterium tuberculosis)
ClpXP from Neisseria meningitidis - Conformation A
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6vfs
Q-score: 0.301
Ripstein ZA, Vahidi S, Houry WA, Rubinstein JL, Kay LE
eLife (2020) 9 [ Pubmed: 31916936 DOI: doi:10.7554/eLife.52158 ]
- Magnesium ion (24 Da, Ligand)
- Atp-dependent clp protease atp-binding subunit clpx, atp-dependent clp protease proteolytic subunit (Complex from Neisseria meningitidis)
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Neisseria meningitidis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Unidentified protein substrate (613 Da, Protein from Escherichia coli BL21(DE3))
- Un-identified protein substrate (Complex from Escherichia coli)
- Atp-dependent clp protease atp-binding subunit clpx (45 kDa, Protein from Neisseria meningitidis)
- Clpxp complex (860 kDa, Complex)
ClpXP from Neisseria meningitidis - Conformation B
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6vfx
Q-score: 0.413
Ripstein ZA, Vahidi S, Houry WA, Rubinstein JL, Kay LE
eLife (2020) 9 [ Pubmed: 31916936 DOI: doi:10.7554/eLife.52158 ]
- Magnesium ion (24 Da, Ligand)
- Atp-dependent clp protease atp-binding subunit clpx, atp-dependent clp protease proteolytic subunit (Complex from Neisseria meningitidis)
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Neisseria meningitidis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-dependent clp protease atp-binding subunit clpx (45 kDa, Protein from Neisseria meningitidis)
- Unidentified peptide substrate (613 Da, Protein from Escherichia coli BL21(DE3))
- Clpxp complex (860 kDa, Complex)
- Unidentified peptide substrate (Complex from Escherichia coli)