Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sb3
Q-score: 0.496
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (10 kDa, Protein from Homo sapiens)
- Structure of oc43 spike in complex with polyclonal fab1 (donor 269) (Complex from Human coronavirus OC43)
- Sapienic acid (254 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7sb4
Q-score: 0.302
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Structure of oc43 spike in complex with polyclonal fab2 (donor 1412) (Complex from Human coronavirus OC43)
- Sapienic acid (254 Da, Ligand)
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7sb5
Q-score: 0.379
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- Structure of oc43 spike in complex with polyclonal fab3 (donor 1412) (Complex from Human coronavirus OC43)
- Palmitic acid (256 Da, Ligand)
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7sbv
Q-score: 0.544
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (9 kDa, Protein from Homo sapiens)
- Sapienic acid (254 Da, Ligand)
- Structure of oc43 spike in complex with polyclonal fab4 (donor 269) (Complex from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7sbw
Q-score: 0.533
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Human polyclonal fab model with polyalanine backbone - heavy chain (10 kDa, Protein from Homo sapiens)
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Structure of oc43 spike in complex with polyclonal fab5 (donor 1051) (Complex from Human coronavirus OC43)
- Sapienic acid (254 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab6 (Donor 1051)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7sbx
Q-score: 0.571
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (10 kDa, Protein from Homo sapiens)
- Sapienic acid (254 Da, Ligand)
- Structure of oc43 spike in complex with polyclonal fab6 (donor 1051) (Complex from Human coronavirus OC43)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of OC43 spike in complex with polyclonal Fab7 (Donor 269)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7sby
Q-score: 0.586
Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Pena AT, Crowe Jr JE, Ward AB
Sci Adv (2022) 8 pp. eabn2911-eabn2911 [ Pubmed: 35507649 DOI: doi:10.1126/sciadv.abn2911 ]
- Spike protein (151 kDa, Protein from Human coronavirus OC43)
- Structure of oc43 spike in complex with polyclonal fab7 (donor 269) (Complex from Human coronavirus OC43)
- Human polyclonal fab model with polyalanine backbone - heavy chain (10 kDa, Protein from Homo sapiens)
- Sapienic acid (254 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Negative stain EM map of Pan-EBOV antibody 520 Fab in complex with EBOV GPdMuc trimer
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe Jr JE
Immunity (2018) 49 pp. 363-374.e10 [ DOI: doi:10.1016/j.immuni.2018.06.018 Pubmed: 30029854 ]
Negative stain EM map of Pan-EBOV antibody 515 Fab in complex with EBOV GPdMuc trimer
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe Jr JE
Immunity (2018) 49 pp. 363-374.e10 [ DOI: doi:10.1016/j.immuni.2018.06.018 Pubmed: 30029854 ]
Bangaru S, Nieusma T, Kose N, Thornburg NJ, Finn JA, Kaplan BS, King HG, Singh V, Lampley RM, Sapparapu G, Cisneros A, Edwards KM, Slaughter JC, Edupuganti S, Lai L, Richt JA, Webby RJ, Ward AB, Crowe JE
JCI Insight (2016) 1 [ Pubmed: 27482543 DOI: doi:10.1172/jci.insight.86673 ]
- A/minnesota/11/2010 h3n2v ha (50 kDa, Complex from Influenza A virus)
- H3v-47 fab (Complex from Homo sapiens)
- Fi6v fab (Complex from Human)