Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab
Reveiz M, Xu K, Lee M, Wang S, Olia AS, Harris DR, Liu K, Liu T, Schaub AJ, Stephens T, Wang Y, Zhang B, Huang R, Tsybovsky Y, Kwong PD, Rawi R
Front Immunol (2024) 15 pp. 1484029-1484029 [ DOI: doi:10.3389/fimmu.2024.1484029 Pubmed: 39611147 ]
- Hiv-1 env trimer complexed with antibody fab (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Antibody acs202 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Antibody acs202 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Antibody fab (Complex from Homo sapiens)
L5A7 Fab bound to Indonesia2005 Hemagglutinin
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8vue
Q-score: 0.442
Olia AS, Prabhakaran M, Harris DR, Cheung CS, Gillespie RA, Gorman J, Hoover A, Morano NC, Ourahmane A, Srikanth A, Wang S, Wu W, Zhou T, Andrews SF, Kanekiyo M, Shapiro L, McDermott AB, Kwong PD
Front Immunol (2024) 15 pp. 1399960-1399960 [ Pubmed: 38873606 DOI: doi:10.3389/fimmu.2024.1399960 ]
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- L5a7 fab light chain (22 kDa, Protein from Homo sapiens)
- L5a7 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Complex of l5a7 fab and indonesia2005 ha (Complex from Homo sapiens)
- Hemagglutinin ha2 chain (19 kDa, Protein from Influenza A virus)
L5A7 Fab bound to 28H6E11 anti-idiotype Fab
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 8vuz
Q-score: 0.426
Olia AS, Prabhakaran M, Harris DR, Cheung CS, Gillespie RA, Gorman J, Hoover A, Morano NC, Ourahmane A, Srikanth A, Wang S, Wu W, Zhou T, Andrews SF, Kanekiyo M, Shapiro L, McDermott AB, Kwong PD
Front Immunol (2024) 15 pp. 1399960-1399960 [ Pubmed: 38873606 DOI: doi:10.3389/fimmu.2024.1399960 ]
- L5a7 fab light chain (22 kDa, Protein from Homo sapiens)
- L5a7 fab heavy chain (24 kDa, Protein from Homo sapiens)
- 28h6e11 fab light chain (24 kDa, Protein from Homo sapiens)
- Complex of l5a7 fab and 28h6e11 fab (Complex from Homo sapiens)
- 28h6e11 fab heavy chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7kc1
Q-score: 0.461
Chuang GY, Shen CH, Cheung CS, Gorman J, Creanga A, Joyce MG, Leung K, Rawi R, Wang L, Yang ES, Yang Y, Zhang B, Zhang Y, Kanekiyo M, Zhou T, DeKosky BJ, Graham BS, Mascola JR, Kwong PD
Front Immunol (2021) 12 pp. 662909-662909 [ DOI: doi:10.3389/fimmu.2021.662909 Pubmed: 34135892 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab light chain (22 kDa, Protein from Homo sapiens)
- Hemagglutinin (38 kDa, Protein from Influenza A virus)
- Fab heavy chain (24 kDa, Protein from Homo sapiens)
- Fusion protein of hemagglutinin and envelope glycoprotein (25 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of srr2899884.46167h+medi8852l fab in complex with victoria ha (Complex from Influenza A virus)
- Cryo-em structure of srr2899884.46167h+medi8852l fab in complex with victoria ha (Complex)