Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8gat
Q-score: 0.562
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ DOI: doi:10.1016/j.immuni.2024.02.003 Pubmed: 38430907 ]
- Fab 1g01, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza virus neuraminidase from a/indiana/10/2011 (h3n2v) in complex with fabs nds.1 and 1g01 (580 kDa, Complex from Homo sapiens)
- Fab 1g01, heavy chain (25 kDa, Protein from Homo sapiens)
- Vasodilator-stimulated phosphoprotein, neuraminidase chimera (51 kDa, Protein from Influenza A virus (A/Indiana/10/2011(H3N2)))
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8gau
Q-score: 0.449
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ DOI: doi:10.1016/j.immuni.2024.02.003 Pubmed: 38430907 ]
- Fab 1g01, light chain (23 kDa, Protein from Homo sapiens)
- Fab nds.1, heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza virus neuraminidase from a/indiana/10/2011 (h3n2v) in complex with fabs nds.1 and 1g01 (580 kDa, Complex from Homo sapiens)
- Fab 1g01, heavy chain (25 kDa, Protein from Homo sapiens)
- Fab nds.1, light chain (23 kDa, Protein from Homo sapiens)
- Vasodilator-stimulated phosphoprotein, neuraminidase chimera (51 kDa, Protein from Influenza A virus (A/Indiana/10/2011(H3N2)))
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8gav
Q-score: 0.605
Lederhofer J, Tsybovsky Y, Nguyen L, Raab JE, Creanga A, Stephens T, Gillespie RA, Syeda HZ, Fisher BE, Skertic M, Yap C, Schaub AJ, Rawi R, Kwong PD, Graham BS, McDermott AB, Andrews SF, King NP, Kanekiyo M
Immunity (2024) 57 pp. 574-586.e7 [ DOI: doi:10.1016/j.immuni.2024.02.003 Pubmed: 38430907 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Influenza virus neuraminidase from a/darwin/09/2021 (h3n2) in complex with fab nds.3 (380 kDa, Complex from Homo sapiens)
- Fab nds.3, heavy chain (24 kDa, Protein from Homo sapiens)
- Fab nds.3, light chain (22 kDa, Protein from Homo sapiens)
- Neuraminidase (51 kDa, Protein from Influenza A virus)
H10ssF: ferritin-based nanoparticle displaying H10 hemagglutinin stabilized stem epitopes
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M
Immunity (2022) 55 pp. 2405-2418.e7 [ DOI: doi:10.1016/j.immuni.2022.10.015 Pubmed: 36356572 ]
- H10ssf (Protein from Helicobacter pylori)
- H10ssf (1 MDa, Complex from Influenza A virus)
Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 6xsk
Q-score: 0.406
Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M
Immunity (2022) 55 pp. 2405-2418.e7 [ DOI: doi:10.1016/j.immuni.2022.10.015 Pubmed: 36356572 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 789-203-3c12 fab heavy and light chains (Cellular component from Macaca mulatta)
- Influenza hemagglutinin (Cellular component from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- 789-203-3c12 fab heavy chain (49 kDa, Protein from Macaca mulatta)
- 789-203-3c12 fab light chain (23 kDa, Protein from Macaca mulatta)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Influenza hemagglutinin si06 trimer in complex with 789-203-3c12 fab (Cellular component)