Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8tni
Q-score: 0.391
Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD
Adv Sci (2024) 11 pp. e2309268-e2309268 [ Pubmed: 38704686 DOI: doi:10.1002/advs.202309268 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of bi-specific antibody cap256l-r27 (36 kDa, Protein from Homo sapiens)
- Heavy chain of bi-specific antibody cap256l-r27 (26 kDa, Protein from Homo sapiens)
- Complex between hiv-1 env bg505 ds-sosip and bi-specific antibody cap256l-r27 (405 kDa, Complex from Homo sapiens)
- Hiv-1 bg505 ds-sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 bg505 ds-sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8ek1
Q-score: 0.473
Tripathi P, Bender MF, Lei H, Da Silva Pereira L, Shen CH, Bonilla B, Dillon M, Ou L, Pancera M, Wang LT, Zhang B, Batista FD, Idris AH, Seder RA, Kwong PD
Structure (2023) 31 pp. 480-491.e4 [ DOI: doi:10.1016/j.str.2023.02.009 Pubmed: 36931276 ]
- L9 fab light chain (23 kDa, Protein from Homo sapiens)
- L9 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Circumsporozoite protein (37 kDa, Protein from Plasmodium falciparum 3D7)
- Pfcsp in complex with antibody l9 (Complex from Homo sapiens)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8eka
Q-score: 0.486
Tripathi P, Bender MF, Lei H, Da Silva Pereira L, Shen CH, Bonilla B, Dillon M, Ou L, Pancera M, Wang LT, Zhang B, Batista FD, Idris AH, Seder RA, Kwong PD
Structure (2023) 31 pp. 480-491.e4 [ DOI: doi:10.1016/j.str.2023.02.009 Pubmed: 36931276 ]
- Circumsporozoite protein (37 kDa, Protein from Plasmodium falciparum 3D7)
- L9 fab heavy chain (24 kDa, Protein from Homo sapiens)
- L9 fab light chain (23 kDa, Protein from Homo sapiens)
- Pfcsp in complex with antibody l9 (Complex from Homo sapiens)
Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8fis
Q-score: 0.453
Zhang B, Gorman J, Kwon YD, Pegu A, Chao CW, Liu T, Asokan M, Bender MF, Bylund T, Damron L, Gollapudi D, Lei P, Li Y, Liu C, Louder MK, McKee K, Olia AS, Rawi R, Schon A, Wang S, Yang ES, Yang Y, Carlton K, Doria-Rose NA, Shapiro L, Seaman MS, Mascola JR, Kwong PD
MABs (2023) 15 pp. 2165390-2165390 [ Pubmed: 36729903 DOI: doi:10.1080/19420862.2023.2165390 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cap256v2ls-j3-3 fab in complex with bg505 ds-sosip.664 (Complex from Human immunodeficiency virus 1)
- J3-vrc26.25 light (37 kDa, Protein from Lama glama)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc26.25 heavy (26 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 4.11 Å
EM Method: Single-particle
Fitted PDBs: 8dw2
Q-score: 0.351
Chonira V, Kwon YD, Gorman J, Case JB, Ku Z, Simeon R, Casner RG, Harris DR, Olia AS, Stephens T, Shapiro L, Bender MF, Boyd H, Teng IT, Tsybovsky Y, Krammer F, Zhang N, Diamond MS, Kwong PD, An Z, Chen Z
Nat Chem Biol (2023) 19 pp. 284-291 [ Pubmed: 36411391 DOI: doi:10.1038/s41589-022-01193-2 ]
- Antibody s309 heavy chain (24 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody cr3022 light chain (24 kDa, Protein from Homo sapiens)
- Antibody s309 light chain (23 kDa, Protein from Homo sapiens)
- Darpin sr22 in complex with sars-cov-2 rbd and antibody fabs, s309 and cr3022 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Antibody cr3022 heavy chain (23 kDa, Protein from Homo sapiens)
- Sr22 (16 kDa, Protein from Escherichia phage EcSzw-2)
Resolution: 4.26 Å
EM Method: Single-particle
Fitted PDBs: 8dw3
Q-score: 0.337
Chonira V, Kwon YD, Gorman J, Case JB, Ku Z, Simeon R, Casner RG, Harris DR, Olia AS, Stephens T, Shapiro L, Bender MF, Boyd H, Teng IT, Tsybovsky Y, Krammer F, Zhang N, Diamond MS, Kwong PD, An Z, Chen Z
Nat Chem Biol (2023) 19 pp. 284-291 [ Pubmed: 36411391 DOI: doi:10.1038/s41589-022-01193-2 ]
- Antibody cr3022 heavy chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Darpin sr16m in complex with sars-cov-2 rbd and antibody fabs, s309 and cr3022 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Antibody s309 light chain (23 kDa, Protein from Homo sapiens)
- Antibody cr3022 light chain (24 kDa, Protein from Homo sapiens)
- Antibody s309 heavy chain (24 kDa, Protein from Homo sapiens)
- Anti-sars-cov-2 darpin sr16m (16 kDa, Protein from Homo sapiens)