ATAT-2 bound MEC-12/MEC-7 microtubule
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8y9f
Q-score: 0.446
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01406-3 Pubmed: 39496813 ]
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Mec-12/mec-7 microtubule in complex with full-length atat-2 (Complex from Caenorhabditis elegans)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
ATAT-2 bound MEC-12/MEC-7 microtubule without acetyl-CoA
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8yaj
Q-score: 0.453
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01406-3 Pubmed: 39496813 ]
- Alpha tat2 bound mec-12/mec-7 microtubules withour acetyl-coa (Complex from Caenorhabditis elegans)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Piperazine-n,n'-bis(2-ethanesulfonic acid) (302 Da, Ligand)
ATAT-2 bound K40Q MEC-12/MEC-7 microtubule
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8yal
Q-score: 0.477
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01406-3 Pubmed: 39496813 ]
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- K40q mec-12/mec-7 microtubule complexed with alpha tat2 (Complex from Caenorhabditis elegans)
- Acetyl coenzyme *a (809 Da, Ligand)
ATAT-2 bound K40R MEC-12/MEC-7 microtubule
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8yar
Q-score: 0.363
Luo J, Lam WH, Yu D, Chao VC, Zopfi MN, Khoo CJ, Zhao C, Yan S, Liu Z, Li XD, Zheng C, Zhai Y, Ti SC
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01406-3 Pubmed: 39496813 ]
- K40r mec-12/mec-7 microtubule in complex with luminal atat-2 (Complex from Caenorhabditis elegans)
- Tubulin beta-1 chain (49 kDa, Protein from Caenorhabditis elegans)
- Tubulin alpha-3 chain (50 kDa, Protein from Caenorhabditis elegans)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Alpha-tubulin n-acetyltransferase 2 (30 kDa, Protein from Caenorhabditis elegans)
- Acetyl coenzyme *a (809 Da, Ligand)
Human menin in complex with H3K79Me2 nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8gpn
Q-score: 0.459
Lin J, Wu Y, Tian G, Yu D, Yang E, Lam WH, Liu Z, Jing Y, Dang S, Bao X, Wong JWH, Zhai Y, Li XD
Science (2023) 379 pp. 717-723 [ Pubmed: 36795828 DOI: doi:10.1126/science.adc9318 ]
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Dna (177-mer) (Complex from Homo sapiens)
- Human menin in complex with nh3k79 dimethylated nucleosome (300 kDa, Complex from Xenopus laevis)
- Isoform 2 of menin (Complex)
- Histone h2a type 1 (13 kDa, Protein from Xenopus laevis)
- Nh3k79 dimethylated nucleosome (Complex)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Dna (177-mer) (54 kDa, DNA from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Isoform 2 of menin (67 kDa, Protein from Homo sapiens)
- Dna (177-mer) (54 kDa, DNA from Homo sapiens)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 5zr1
Q-score: 0.547
Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK
Nature (2018) 559 pp. 217-222 [ DOI: doi:10.1038/s41586-018-0293-x Pubmed: 29973722 ]
- 72bp-oring dna, acs305, a-rich (22 kDa, DNA from Saccharomyces cerevisiae)
- Origin recognition complex subunit 5 (55 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- 72bp-oring dna, acs305, t-rich (22 kDa, DNA from Saccharomyces cerevisiae)
- Origin recognition complex subunit 6 (50 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Origin recognition complex subunit 3 (72 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Origin recognition complex subunit 4 (60 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Origin recognition complex subunit 2 (71 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Origin recognition complex subunit 1 (104 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Saccharomyces cerevisiae origin recognition complex bound to a 72-bp origin dna containing acs and b1 element (Complex from Saccharomyces cerevisiae)