Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6pkv
Q-score: 0.319
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ DOI: doi:10.1038/s41467-019-11733-5 Pubmed: 31431622 ]
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6pkw
Q-score: 0.296
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ DOI: doi:10.1038/s41467-019-11733-5 Pubmed: 31431622 ]
Cryo-EM structure of the zebrafish TRPM2 channel in the presence of ADPR and Ca2+
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6pkx
Q-score: 0.317
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ DOI: doi:10.1038/s41467-019-11733-5 Pubmed: 31431622 ]
- Transient receptor potential cation channel subfamily m member 2 (167 kDa, Protein from Danio rerio)
- Calcium ion (40 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 2 (Complex from Danio rerio)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
Cryo-EM structure of the zebrafish TRPM2 channel in the presence of Ca2+
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6d73
Q-score: 0.365
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ DOI: doi:10.1038/s41467-019-11733-5 Pubmed: 31431622 ]
Structure of the human TRPV3 channel in the apo conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6mho
Q-score: 0.446
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of the human TRPV3 channel in a putative sensitized conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6mhs
Q-score: 0.392
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C4 symmetry
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6mhv
Q-score: 0.481
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhw
Q-score: 0.391
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhx
Q-score: 0.372
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of the cold- and menthol-sensing ion channel TRPM8
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6bpq
Q-score: 0.395
Yin Y, Wu M, Zubcevic L, Borschel WF, Lander GC, Lee SY
Science (2018) 359 pp. 237-241 [ DOI: doi:10.1126/science.aan4325 Pubmed: 29217583 ]