Human DNA polymerase theta helicase domain tetramer in the apo form
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9bh6
Q-score: 0.488
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain (400 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain dimer in the apo form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bh7
Q-score: 0.436
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Human dna polymerase theta helicase domain (200 kDa, Complex from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9bh8
Q-score: 0.401
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bh9
Q-score: 0.422
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bha
Q-score: 0.43
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8flj
Q-score: 0.35
Santiago-Frangos A, Henriques WS, Wiegand T, Gauvin CC, Buyukyoruk M, Graham AB, Wilkinson RA, Triem L, Neselu K, Eng ET, Lander GC, Wiedenheft B
Nat Struct Mol Biol (2023) 30 pp. 1675-1685 [ Pubmed: 37710013 DOI: doi:10.1038/s41594-023-01097-2 ]
- Crispr leader, sense strand of dna (42 kDa, DNA from Pseudomonas aeruginosa PA14)
- Crispr-associated nuclease/helicase cas3 subtype i-f/ypest (121 kDa, Protein from Pseudomonas aeruginosa PA14)
- Integration host factor subunit alpha (11 kDa, Protein from Pseudomonas aeruginosa PA14)
- Ihf heterodimer (Complex from Pseudomonas aeruginosa PA14)
- Integration host factor subunit beta (10 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr-associated endonuclease cas1 (38 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr leader, repeat, and prespacer dna annealed to mimic a half-site integration intermediate. (Complex)
- Crispr repeat and prespacer, sense strand of dna (18 kDa, DNA from synthetic construct)
- Crispr leader and repeat, anti-sense strand of dna (52 kDa, DNA from Pseudomonas aeruginosa PA14)
- Cas1-cas2/3 heterohexameric integrase (Complex from Pseudomonas aeruginosa PA14)
- Cas1-cas2/3 integrase and ihf bound to crispr leader, repeat and foreign dna (122 kDa, Complex)
- Prespacer, anti-sense strand of dna (8 kDa, DNA from synthetic construct)
Negative stain reconstruction of human autophagy associated protein complex, ATG2A-WIPI4
Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T
PNAS (2018) 115 pp. E9792-E9801 [ Pubmed: 30185561 DOI: doi:10.1073/pnas.1811874115 ]
- Complex between human atg2a and wipi4 proteins. (250 kDa, Complex from Homo sapiens)
Negative stain reconstruction of human autophagy associated protein, ATG2A
Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T
PNAS (2018) 115 pp. E9792-E9801 [ Pubmed: 30185561 DOI: doi:10.1073/pnas.1811874115 ]
- Human atg2a protein (200 kDa, Complex from Homo sapiens)
Cryo-EM reconstruction of fully-mature capsid of Nudaurelia capensis omega virus (NwV)
Matsui T, Lander GC, Khayat R, Johnson JE
PNAS (2010) 107 pp. 14111-14115 [ DOI: doi:10.1073/pnas.1004221107 Pubmed: 20660783 ]
Matsui T, Lander GC, Khayat R, Johnson JE
PNAS (2010) 107 pp. 14111-14115 [ DOI: doi:10.1073/pnas.1004221107 Pubmed: 20660783 ]