Human mitochondrial LONP1 in complex with Bortezomib
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7krz
Q-score: 0.572
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ DOI: doi:10.1038/s41467-021-23495-0 Pubmed: 34050165 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Lon protease homolog, mitochondrial (59 kDa, Protein from Homo sapiens)
- N-[(1r)-1-(dihydroxyboryl)-3-methylbutyl]-n-(pyrazin-2-ylcarbonyl)-l-phenylalaninamide (384 Da, Ligand)
- Human mitochondrial lonp1 in complex with bortezomib (462 kDa, Complex from Homo sapiens)
- Endogenous co-purified substrate (1 kDa, Protein from Escherichia coli BL21(DE3))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Substrate-free human mitochondrial LONP1
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ksl
Q-score: 0.506
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ DOI: doi:10.1038/s41467-021-23495-0 Pubmed: 34050165 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Substrate-free human mitochondrial lonp1 (462 kDa, Complex from Homo sapiens)
- Lon protease homolog, mitochondrial (58 kDa, Protein from Homo sapiens)
Human mitochondrial LONP1 with endogenous substrate
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ksm
Q-score: 0.568
Shin M, Watson ER, Song AS, Mindrebo JT, Novick SJ, Griffin PR, Wiseman RL, Lander GC
Nat Commun (2021) 12 pp. 3239-3239 [ DOI: doi:10.1038/s41467-021-23495-0 Pubmed: 34050165 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Lon protease homolog, mitochondrial (59 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Unidentified endogenous substrate (1 kDa, Protein from Escherichia coli BL21(DE3))
- Human mitochondrial lonp1 with endogenous substrate (462 kDa, Complex from Homo sapiens)
Structure of the human TRPV3 channel in the apo conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6mho
Q-score: 0.446
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of the human TRPV3 channel in a putative sensitized conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6mhs
Q-score: 0.392
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C4 symmetry
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6mhv
Q-score: 0.481
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhw
Q-score: 0.391
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhx
Q-score: 0.372
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]