Cryo-EM structure of LKB1-STRADalpha-MO25alpha heterocomplex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8vsu
Q-score: 0.575
Chan LM, Courteau BJ, Maker A, Wu M, Basanta B, Mehmood H, Bulkley D, Joyce D, Lee BC, Mick S, Czarnik C, Gulati S, Lander GC, Verba KA
J Struct Biol (2024) 216 pp. 108108-108108 [ Pubmed: 38944401 DOI: doi:10.1016/j.jsb.2024.108108 ]
- Isoform 3 of ste20-related kinase adapter protein alpha (47 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Serine/threonine-protein kinase stk11 (50 kDa, Protein from Homo sapiens)
- Calcium-binding protein 39 (41 kDa, Protein from Homo sapiens)
- Heterotrimeric complex of serine/threonine kinase lkb1 with psuedokinase strada and scaffolding mo25a (140 kDa, Complex from Homo sapiens)
Apoferritin at 100 keV on Alpine detector with a side-entry cryoholder
Chan LM, Courteau BJ, Maker A, Wu M, Basanta B, Mehmood H, Bulkley D, Joyce D, Lee BC, Mick S, Czarnik C, Gulati S, Lander GC, Verba KA
J Struct Biol (2024) 216 pp. 108108-108108 [ Pubmed: 38944401 DOI: doi:10.1016/j.jsb.2024.108108 ]
- Heavy chain apoferritin from mouse (Protein from Mus musculus)
- Heavy chain apoferritin from mouse (487 kDa, Complex from Mus musculus)
Aldolase at 100 keV on the Alpine detector with a side-entry cryoholder
Human 20S proteasome bound to an engineered 11S (PA26) activator
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6xmj
Q-score: 0.584
Opoku-Nsiah KA, de la Pena AH, Williams SK, Chopra N, Sali A, Lander GC, Gestwicki JE
Nat Commun (2022) 13 pp. 1226-1226 [ DOI: doi:10.1038/s41467-022-28864-x Pubmed: 35264557 ]
- Proteasome subunit alpha type-5 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (26 kDa, Protein from Homo sapiens)
- Mutant pa26 (Complex from Trypanosoma brucei)
- Proteasome subunit beta type-5 (22 kDa, Protein from Homo sapiens)
- Pa26-bound proteasome (Complex)
- Proteasome (Complex from Homo sapiens)
- Proteasome subunit alpha type-3 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (21 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (23 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (23 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (24 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome activator protein pa26 (24 kDa, Protein from Trypanosoma brucei)