Cryo-EM structure of LKB1-STRADalpha-MO25alpha heterocomplex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8vsu
Q-score: 0.575
Chan LM, Courteau BJ, Maker A, Wu M, Basanta B, Mehmood H, Bulkley D, Joyce D, Lee BC, Mick S, Czarnik C, Gulati S, Lander GC, Verba KA
J Struct Biol (2024) 216 pp. 108108-108108 [ Pubmed: 38944401 DOI: doi:10.1016/j.jsb.2024.108108 ]
- Isoform 3 of ste20-related kinase adapter protein alpha (47 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Serine/threonine-protein kinase stk11 (50 kDa, Protein from Homo sapiens)
- Calcium-binding protein 39 (41 kDa, Protein from Homo sapiens)
- Heterotrimeric complex of serine/threonine kinase lkb1 with psuedokinase strada and scaffolding mo25a (140 kDa, Complex from Homo sapiens)
Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6pkv
Q-score: 0.319
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ Pubmed: 31431622 DOI: doi:10.1038/s41467-019-11733-5 ]
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6pkw
Q-score: 0.296
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ Pubmed: 31431622 DOI: doi:10.1038/s41467-019-11733-5 ]
Cryo-EM structure of the zebrafish TRPM2 channel in the presence of ADPR and Ca2+
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6pkx
Q-score: 0.317
Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY
Nat Commun (2019) 10 pp. 3740-3740 [ Pubmed: 31431622 DOI: doi:10.1038/s41467-019-11733-5 ]
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Transient receptor potential cation channel subfamily m member 2 (Complex from Danio rerio)
- Transient receptor potential cation channel subfamily m member 2 (167 kDa, Protein from Danio rerio)
Structure of the human TRPV3 channel in the apo conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6mho
Q-score: 0.446
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of the human TRPV3 channel in a putative sensitized conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6mhs
Q-score: 0.392
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C4 symmetry
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6mhv
Q-score: 0.481
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhw
Q-score: 0.391
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mhx
Q-score: 0.372
Zubcevic L, Herzik Jr MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY
Nat Commun (2018) 9 pp. 4773-4773 [ Pubmed: 30429472 DOI: doi:10.1038/s41467-018-07117-w ]
Cryo-EM structure of a mitochondrial calcium uniporter
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6dt0
Q-score: 0.402
Yoo J, Wu M, Yin Y, Herzik Jr MA, Lander GC, Lee SY
Science (2018) 361 pp. 506-511 [ DOI: doi:10.1126/science.aar4056 Pubmed: 29954988 ]
- Calcium ion (40 Da, Ligand)
- Mitochondrial calcium uniporter (52 kDa, Protein from Neurospora crassa)
- Mitochondrial calcium uniporter (Complex from Neurospora crassa)