Human Mitochondrial LONP1 Stall State + casein
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 9cc3
Q-score: 0.489
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.24.600538 Pubmed: 38979310 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Lon protease homolog, mitochondrial (97 kDa, Protein from Homo sapiens)
- Endogenous co-purified substrate modeled as unknown residues (2 kDa, Protein from Escherichia coli 'BL21-Gold(DE3)pLysS AG')
- Lonp1 closed state in complex with casein (583 kDa, Complex from Homo sapiens)
Human DNA polymerase theta helicase domain tetramer in the apo form
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9bh6
Q-score: 0.488
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain (400 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain dimer in the apo form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bh7
Q-score: 0.436
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Human dna polymerase theta helicase domain (200 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9bh8
Q-score: 0.401
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bh9
Q-score: 0.422
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9bha
Q-score: 0.43
Zerio CJ, Bai Y, Sosa-Alvarado BA, Guzi T, Lander GC
To Be Published
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
- Human dna polymerase theta helicase domain bound to stem-loop dna with microhomology in the 3' overhang (20 kDa, Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (17 kDa, DNA from synthetic construct)
- Human dna polymerase theta helicase domain (Complex from Homo sapiens)
- Stem-loop dna with microhomology in the 3' overhang (Complex from Homo sapiens)
Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8flj
Q-score: 0.35
Santiago-Frangos A, Henriques WS, Wiegand T, Gauvin CC, Buyukyoruk M, Graham AB, Wilkinson RA, Triem L, Neselu K, Eng ET, Lander GC, Wiedenheft B
Nat Struct Mol Biol (2023) 30 pp. 1675-1685 [ DOI: doi:10.1038/s41594-023-01097-2 Pubmed: 37710013 ]
- Crispr repeat and prespacer, sense strand of dna (18 kDa, DNA from synthetic construct)
- Cas1-cas2/3 heterohexameric integrase (Complex from Pseudomonas aeruginosa PA14)
- Crispr-associated nuclease/helicase cas3 subtype i-f/ypest (121 kDa, Protein from Pseudomonas aeruginosa PA14)
- Integration host factor subunit alpha (11 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr leader, repeat, and prespacer dna annealed to mimic a half-site integration intermediate. (Complex)
- Ihf heterodimer (Complex from Pseudomonas aeruginosa PA14)
- Cas1-cas2/3 integrase and ihf bound to crispr leader, repeat and foreign dna (122 kDa, Complex)
- Integration host factor subunit beta (10 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr leader, sense strand of dna (42 kDa, DNA from Pseudomonas aeruginosa PA14)
- Crispr leader and repeat, anti-sense strand of dna (52 kDa, DNA from Pseudomonas aeruginosa PA14)
- Crispr-associated endonuclease cas1 (38 kDa, Protein from Pseudomonas aeruginosa PA14)
- Prespacer, anti-sense strand of dna (8 kDa, DNA from synthetic construct)
Mouse heavy chain apoferritin determined in presence of 20% glycerol (300keV)
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Apoferritin (Protein from Mus musculus)
- Apoferritin (487 kDa, Complex from Mus musculus)
Rabbit muscle aldolase determined in the presence of 20% v/v glycerol.
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Aldolase (157 kDa, Complex from Oryctolagus cuniculus)
- Aldolase (Protein from Oryctolagus cuniculus)
Human 20S proteasome bound to an engineered 11S (PA26) activator
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6xmj
Q-score: 0.584
Opoku-Nsiah KA, de la Pena AH, Williams SK, Chopra N, Sali A, Lander GC, Gestwicki JE
Nat Commun (2022) 13 pp. 1226-1226 [ Pubmed: 35264557 DOI: doi:10.1038/s41467-022-28864-x ]
- Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-5 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-7 (23 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-6 (21 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-1 (23 kDa, Protein from Homo sapiens)
- Mutant pa26 (Complex from Trypanosoma brucei)
- Pa26-bound proteasome (Complex)
- Proteasome subunit alpha type-4 (28 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-5 (25 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-1 (26 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-3 (27 kDa, Protein from Homo sapiens)
- Proteasome subunit beta type-4 (24 kDa, Protein from Homo sapiens)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
- Proteasome activator protein pa26 (24 kDa, Protein from Trypanosoma brucei)
- Proteasome (Complex from Homo sapiens)