Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
- Tubulin alpha-1b chain (Protein from Homo sapiens)
- Tubulin polyglutamylase ttll6 (Protein from Mus musculus)
- Ttll6 bound to unmodified human microtubules (300 kDa, Complex)
- Tubulin beta-i/ivb chain (Protein from Homo sapiens)
- Tubulin polyglutamylase ttll6 (Complex from Mus musculus)
- Tubulin alpha-1b, betai and betaivb (Complex from Homo sapiens)
Map of Tubulin Tyrosine Ligase Like 6
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) 20 pp. 1493-1504 [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8t42
Q-score: 0.395
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) 20 pp. 1493-1504 [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Homo sapiens)
- Tubulin alpha-1b chain (50 kDa, Protein from Homo sapiens)
- Ttll6 bound to unmodified human microtubules (300 kDa, Complex)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Tubulin polyglutamylase ttll6 (59 kDa, Protein from Mus musculus)
- Tubulin alpha-1b chain, tubulin betai chain (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Tubulin polyglutamylase ttll6 (Complex from Mus musculus)
Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8flj
Q-score: 0.35
Santiago-Frangos A, Henriques WS, Wiegand T, Gauvin CC, Buyukyoruk M, Graham AB, Wilkinson RA, Triem L, Neselu K, Eng ET, Lander GC, Wiedenheft B
Nat Struct Mol Biol (2023) 30 pp. 1675-1685 [ DOI: doi:10.1038/s41594-023-01097-2 Pubmed: 37710013 ]
- Crispr repeat and prespacer, sense strand of dna (18 kDa, DNA from synthetic construct)
- Cas1-cas2/3 heterohexameric integrase (Complex from Pseudomonas aeruginosa PA14)
- Crispr-associated nuclease/helicase cas3 subtype i-f/ypest (121 kDa, Protein from Pseudomonas aeruginosa PA14)
- Integration host factor subunit alpha (11 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr leader, repeat, and prespacer dna annealed to mimic a half-site integration intermediate. (Complex)
- Ihf heterodimer (Complex from Pseudomonas aeruginosa PA14)
- Cas1-cas2/3 integrase and ihf bound to crispr leader, repeat and foreign dna (122 kDa, Complex)
- Integration host factor subunit beta (10 kDa, Protein from Pseudomonas aeruginosa PA14)
- Crispr leader, sense strand of dna (42 kDa, DNA from Pseudomonas aeruginosa PA14)
- Crispr leader and repeat, anti-sense strand of dna (52 kDa, DNA from Pseudomonas aeruginosa PA14)
- Crispr-associated endonuclease cas1 (38 kDa, Protein from Pseudomonas aeruginosa PA14)
- Prespacer, anti-sense strand of dna (8 kDa, DNA from synthetic construct)
Mouse heavy chain apoferritin determined in presence of 1.66% glycerol.
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Apoferritin (Protein from Mus musculus)
- Apoferritin (487 kDa, Complex from Mus musculus)
Mouse heavy chain apoferritin determined in presence of 20% glycerol (300keV)
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Apoferritin (Protein from Mus musculus)
- Apoferritin (487 kDa, Complex from Mus musculus)
Rabbit muscle aldolase determined in presence of 20% v/v glycerol
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Aldolase (157 kDa, Complex from Oryctolagus cuniculus)
- Aldolase (Protein from Oryctolagus cuniculus)
Rabbit muscle aldolase determined in the presence of 20% v/v glycerol.
Basanta B, Hirschi MM, Grotjahn DA, Lander GC
Acta Crystallogr D Struct Biol (2022) 78 pp. 124-135 [ Pubmed: 34981768 DOI: doi:10.1107/S2059798321012110 ]
- Aldolase (157 kDa, Complex from Oryctolagus cuniculus)
- Aldolase (Protein from Oryctolagus cuniculus)
Single-particle cryo-EM reconstruction of rabbit muscle aldolase using 200 keV
J Struct Biol X (2020) 4 pp. 100020-100020 [ DOI: doi:10.1016/j.yjsbx.2020.100020 Pubmed: 32647824 ]
- Water (18 Da, Ligand)
- Fructose-bisphosphate aldolase a (37 kDa, Protein from Oryctolagus cuniculus)
- Aldolase from rabbit muscle (150 kDa, Complex from Oryctolagus cuniculus)
Single-particle cryo-EM reconstruction of mouse heavy chain apoferritin at 200 keV
J Struct Biol X (2020) 4 pp. 100020-100020 [ DOI: doi:10.1016/j.yjsbx.2020.100020 Pubmed: 32647824 ]
- Ferritin heavy chain (20 kDa, Protein from Mus musculus)
- Heavy chain apoferritin from mouse (505 kDa, Complex from Mus musculus)
- Water (18 Da, Ligand)