BJOX2000.664 trimer in complex with Fab fragment of broadly neutralizing HIV antibody PGT145
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 8jtd
Q-score: 0.211
Hodge EA, Chatterjee A, Chen C, Naika GS, Laohajaratsang M, Mangala Prasad V, Lee KK
Npj Viruses (2023) 1 pp. 2-2 [ Pubmed: 38665238 DOI: doi:10.1038/s44298-023-00002-4 ]
- Bjox2000.664 trimer in complex with broadly neutralizing hiv antibody pgt145 (Complex from Human immunodeficiency virus 1)
- Gp41 protein of hiv envelope trimer (17 kDa, Protein from Human immunodeficiency virus 1)
- Gp120 protein of hiv envelope trimer (54 kDa, Protein from Human immunodeficiency virus 1)
- Pgt145 antibody fragment, heavy chain (28 kDa, Protein from Homo sapiens)
- Pgt145 antibody fragment, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
CNE55.664 trimer in complex with broadly neutralizing HIV antibody PGT145
Resolution: 5.14 Å
EM Method: Single-particle
Fitted PDBs: 8jtm
Q-score: 0.166
Hodge EA, Chatterjee A, Chen C, Naika GS, Laohajaratsang M, Mangala Prasad V, Lee KK
Npj Viruses (2023) 1 pp. 2-2 [ Pubmed: 38665238 DOI: doi:10.1038/s44298-023-00002-4 ]
- Cne55.664 trimer in complex with broadly neutralizing hiv antibody pgt145 (Complex from Human immunodeficiency virus 1)
- Pgt145 antibody fragment, heavy chain (28 kDa, Protein from Homo sapiens)
- Gp120 protein of hiv envelope trimer (54 kDa, Protein from Human immunodeficiency virus 1)
- Pgt145 antibody fragment, light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gp41 protein of hiv envelope trimer (17 kDa, Protein from Human immunodeficiency virus 1)
Influenza Neuraminidase N1-CA09-sNAp-155
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7u2q
Q-score: 0.514
Ellis D, Lederhofer J, Acton OJ, Tsybovsky Y, Kephart S, Yap C, Gillespie RA, Creanga A, Olshefsky A, Stephens T, Pettie D, Murphy M, Sydeman C, Ahlrichs M, Chan S, Borst AJ, Park YJ, Lee KK, Graham BS, Veesler D, King NP, Kanekiyo M
Nat Commun (2022) 13 pp. 1825-1825 [ Pubmed: 35383176 DOI: doi:10.1038/s41467-022-29416-z ]
- Influenza n1-ca09-snap-155 (42 kDa, Protein from Influenza A virus)
- Structure-based design of an engineered influenza neuraminidase tetramer (210 MDa, Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Influenza Neuraminidase N1-MI15-sNAp-174
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7u2t
Q-score: 0.505
Ellis D, Lederhofer J, Acton OJ, Tsybovsky Y, Kephart S, Yap C, Gillespie RA, Creanga A, Olshefsky A, Stephens T, Pettie D, Murphy M, Sydeman C, Ahlrichs M, Chan S, Borst AJ, Park YJ, Lee KK, Graham BS, Veesler D, King NP, Kanekiyo M
Nat Commun (2022) 13 pp. 1825-1825 [ Pubmed: 35383176 DOI: doi:10.1038/s41467-022-29416-z ]
- Influenza n1-mi15-snap-174 (42 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure-based design of an engineered influenza neuraminidase tetramer (210 MDa, Complex from Influenza A virus)
Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664
Resolution: 4.15 Å
EM Method: Single-particle
Fitted PDBs: 7n65
Q-score: 0.348
Shipley MM, Mangala Prasad V, Doepker LE, Dingens AS, Ralph DK, Harkins E, Dhar A, Arenz D, Chohan V, Weight H, Mandaliya K, Bloom JD, Matsen Iv F, Lee KK, Overbaugh JM
eLife (2021) 10 [ Pubmed: 34263727 DOI: doi:10.7554/eLife.68110 ]
- Fab qa013.2 light chain, , variable region (11 kDa, Protein from Homo sapiens)
- Complex of hiv-1 envelope protein with super-infection fab qa013.2 (500 kDa, Complex from Human immunodeficiency virus 1)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Fab qa013.2 heavy chain, variable region (14 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (18 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp41 (56 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7kna
Q-score: 0.499
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ DOI: doi:10.1038/s41586-021-03365-x Pubmed: 33762730 ]
Cryo-EM structure of BG505.SOSIP.664 in complex with BF520.1 antigen binding fragment
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6mn7
Q-score: 0.049
Simonich CA, Doepker L, Ralph D, Williams JA, Dhar A, Yaffe Z, Gentles L, Small CT, Oliver B, Vigdorovich V, Mangala Prasad V, Nduati R, Sather DN, Lee KK, Matsen Iv FA, Overbaugh J
Nat Commun (2019) 10 pp. 2190-2190 [ Pubmed: 31097697 DOI: doi:10.1038/s41467-019-09481-7 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Bf520.1 fab variable region (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of bf520.1 fab in complex with bg505.sosip.664 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)