Cryo-EM structure of Lumazine synthase nanoparticle linked to VP8* antigen
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8f25
Q-score: 0.586
Roier S, Mangala Prasad V, McNeal MM, Lee KK, Petsch B, Rauch S
NPJ Vaccines (2023) 8 pp. 190-190 [ DOI: doi:10.1038/s41541-023-00790-z Pubmed: 38129390 ]
Sub-tomogram averaged map of full-length post-fusion CHIKV E1 glycoprotein trimer
Resolution: 27.2 Å
EM Method: Subtomogram averaging
Fitted PDBs: 8d87
Q-score: 0.029
Mangala Prasad V, Blijleven JS, Smit JM, Lee KK
Nat Commun (2022) 13 pp. 4772-4772 [ Pubmed: 35970990 DOI: doi:10.1038/s41467-022-32431-9 ]
- Phosphate ion (94 Da, Ligand)
- Spike glycoprotein e1 (42 kDa, Protein from Chikungunya virus strain S27-African prototype)
- Sub-tomogram averaged map of post-fusion e1 glycoprotein trimer from chikungunya virus (150 kDa, Complex from Chikungunya virus strain S27-African prototype)
- Bromide ion (79 Da, Ligand)
- Holmium atom (164 Da, Ligand)
- Water (18 Da, Ligand)
Sub-tomogram averaged structure of HIV-1 Envelope protein in native membrane
Resolution: 9.1 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7ska
Q-score: 0.067
Mangala Prasad V, Leaman DP, Lovendahl KN, Croft JT, Benhaim MA, Hodge EA, Zwick MB, Lee KK
Cell (2022) 185 pp. 641-653.e17 [ DOI: doi:10.1016/j.cell.2022.01.013 Pubmed: 35123651 ]
- Human immunodeficiency virus 1 (430 kDa, Virus from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Alpha-l-fucopyranose (164 Da, Ligand)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664
Resolution: 4.15 Å
EM Method: Single-particle
Fitted PDBs: 7n65
Q-score: 0.348
Shipley MM, Mangala Prasad V, Doepker LE, Dingens AS, Ralph DK, Harkins E, Dhar A, Arenz D, Chohan V, Weight H, Mandaliya K, Bloom JD, Matsen Iv F, Lee KK, Overbaugh JM
eLife (2021) 10 [ DOI: doi:10.7554/eLife.68110 Pubmed: 34263727 ]
- Fab qa013.2 light chain, , variable region (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp41 (18 kDa, Protein from Human immunodeficiency virus 1)
- Fab qa013.2 heavy chain, variable region (14 kDa, Protein from Homo sapiens)
- Complex of hiv-1 envelope protein with super-infection fab qa013.2 (500 kDa, Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (56 kDa, Protein from Human immunodeficiency virus 1)
- Alpha-d-mannopyranose (180 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7kna
Q-score: 0.499
Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, Baker D, Mascola JR, Veesler D, Graham BS, King NP, Kanekiyo M
Nature (2021) 592 pp. 623-628 [ Pubmed: 33762730 DOI: doi:10.1038/s41586-021-03365-x ]
Cryo-EM structure of BG505.SOSIP.664 in complex with BF520.1 antigen binding fragment
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6mn7
Q-score: 0.049
Simonich CA, Doepker L, Ralph D, Williams JA, Dhar A, Yaffe Z, Gentles L, Small CT, Oliver B, Vigdorovich V, Mangala Prasad V, Nduati R, Sather DN, Lee KK, Matsen Iv FA, Overbaugh J
Nat Commun (2019) 10 pp. 2190-2190 [ Pubmed: 31097697 DOI: doi:10.1038/s41467-019-09481-7 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of bf520.1 fab in complex with bg505.sosip.664 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Bf520.1 fab variable region (25 kDa, Protein from Homo sapiens)