Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz4
Q-score: 0.368
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Sars-cov-2 s 6p in complex with m8a-3 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-3 fab light chain (23 kDa, Protein from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab vh and vl domains (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7uz5
Q-score: 0.355
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-6 fab vh and vl domains (Complex from Mus musculus)
- M8a-6 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-6 fab heavy chain (25 kDa, Protein from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-6 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-6 fab light chain (23 kDa, Protein from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-28
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uz6
Q-score: 0.477
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-28 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-28 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-28 fab heavy chain (25 kDa, Protein from Mus musculus)
- M8a-28 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-28 fab vh and vl domains (Complex from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uz7
Q-score: 0.36
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz8
Q-score: 0.35
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uz9
Q-score: 0.289
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- M8a-34 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-34 fab heavy chain (25 kDa, Protein from Mus musculus)
- M8a-34 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-34 fab vh and vl domains (Complex from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 s 6p in complex with m8a-34 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uza
Q-score: 0.377
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Hsw-1 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with hsw-1 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Hsw-1 fab light chain (23 kDa, Protein from Mus musculus)
- Hsw-1 fab heavy chain (25 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Hsw-1 fab vh and vl domains (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S S1 doamin in complex with the mouse antibody Fab fragment, HSW-2
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7uzb
Q-score: 0.334
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Hsw-2 fab heavy chain (24 kDa, Protein from Mus musculus)
- Hsw-2 fab vh and vl domains (Complex from Mus musculus)
- Hsw-2 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein s1 domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hsw-2 fab ch1 and cl domains (Complex from Mus musculus)
- Sars-cov-2 s 6p in complex with hsw-2 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ucg
Q-score: 0.411
Barnes CO, Schoofs T, Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H, Schommers P, Suh-Toma N, Lee YE, Cetrulo Lorenzi JC, Piechocka-Trocha A, Scheid JF, West Jr AP, Walker BD, Seaman MS, Klein F, Nussenzweig MC, Bjorkman PJ
Sci Adv (2022) 8 pp. eabp8155-eabp8155 [ Pubmed: 35960796 DOI: doi:10.1126/sciadv.abp8155 ]
- 10-1074 fab heavy chain (26 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of du422 sosip trimer bound to 10-1074 and bg24 fab fragments (650 kDa, Complex from Homo sapiens)
- 10-1074 light chain (23 kDa, Protein from Homo sapiens)
- Bg24 light chain (21 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Bg24 cdrh2-v2 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp160 (56 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uap
Q-score: 0.384
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Ben Tanfous T, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC
Immunity (2022) 55 pp. 998-1012.e8 [ DOI: doi:10.1016/j.immuni.2022.04.003 Pubmed: 35447092 ]
- C1520 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C1520 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p + c1520 fab fragments (700 kDa, Complex from Homo sapiens)