Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 9dzu
Q-score: 0.479
Chen X, Duan HD, Hoy MJ, Koteva K, Spitzer M, Guitor AK, Puumala E, Hu G, Yiu B, Chou S, Bian Z, Guo ABY, Sun S, Robbins N, Cook MA, Truant R, MacNeil LT, Brown ED, Kronstad JW, Cowen LE, Heitman J, Li H, Wright GD
bioRxiv (2025) [ Pubmed: 39829750 DOI: doi:10.1101/2025.01.06.630955 ]
- Beryllium trifluoride ion (66 Da, Ligand)
- Phospholipid-transporting atpase (176 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Magnesium ion (24 Da, Ligand)
- (3r,4r,5s)-3,4-dihydroxy-5-[(1r,2r,3s,4s,5r,6r,10e,14z,16e,18z)-1,2,3,4,5-pentahydroxy-6,20,20-trimethylhenicosa-10,14,16,18-tetraen-1-yl]oxolan-2-one (526 Da, Ligand)
- Apt1-cdc50 heterodimer bound with butyrolactol a (222 kDa, Complex from Cryptococcus neoformans var. grubii H99)
- Transcription regulator (45 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the C. neoformans lipid flippase Apt1-Cdc50 in the E1 state
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 9dzv
Q-score: 0.399
Chen X, Duan HD, Hoy MJ, Koteva K, Spitzer M, Guitor AK, Puumala E, Hu G, Yiu B, Chou S, Bian Z, Guo ABY, Sun S, Robbins N, Cook MA, Truant R, MacNeil LT, Brown ED, Kronstad JW, Cowen LE, Heitman J, Li H, Wright GD
bioRxiv (2025) [ Pubmed: 39829750 DOI: doi:10.1101/2025.01.06.630955 ]
- Phospholipid-transporting atpase (176 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Magnesium ion (24 Da, Ligand)
- Transcription regulator (45 kDa, Protein from Cryptococcus neoformans var. grubii H99)
- Apt1-cdc50 heterodimer (222 kDa, Complex from Cryptococcus neoformans var. grubii H99)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8znz
Q-score: 0.547
Xu JG, Chen S, He Y, Zhu X, Wang Y, Ye Z, Zhou JC, Wu X, Zhang L, Ren X, Jia H, Yu H, Wei X, Feng Y, Chen X, Cui X, Pan X, Wang S, Xia S, Shang H, Pu Y, Xu W, Li H, Chen Q, Chen Z, Wang M, Yan X, Shi H, Li M, Xia Y, Bellelli R, Dong S, He J, Huang J, Cai CL, Zhu X, Zhan Y, Wan L
Nat Commun (2024) 15 pp. 10872-10872 [ DOI: doi:10.1038/s41467-024-55207-9 Pubmed: 39738003 ]
- 5'-nucleotidase (58 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Hb0039 fab light chain (11 kDa, Protein from Homo sapiens)
- Cd73 complexed with hb0017 antibody coaktail (630 kDa, Complex from Homo sapiens)
- Hb0039 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Hb0038 fab light chain (11 kDa, Protein from Homo)
- Hb0038 fab heavy chain (13 kDa, Protein from Homo)
Single particle cryoEM data of Human OGG1 bound to a 35-bp DNA with an 8-oxoG in the middle
Single particle cryoEM data of Nucleosome core particle containing an 8-oxoG damage site
Structure of the extracellular domain of Protein Sevenless
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 9bhx
Q-score: 0.36
Zhang J, Tsutsui Y, Li H, Li T, Wang Y, Laraki S, Alarcon-Frias S, Stayrook SE, Klein DE
Nat Commun (2025) 16 pp. 808-808 [ DOI: doi:10.1038/s41467-025-55943-6 Pubmed: 39827240 ]
- Protein sevenless (Cell from Drosophila melanogaster)
- Protein sevenless (181 kDa, Protein from Drosophila melanogaster)
DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006
Resolution: 3.79 Å
EM Method: Single-particle
Fitted PDBs: 8rl5
Q-score: 0.217
Yi G, Mamalis D, Ye M, Carrique L, Fairhead M, Li H, Duerr K, Zhang P, Sauer DB, von Delft F, Davis BG, Gilbert RJC
To Be Published
- Atp-dependent dna helicase q5 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Recql5 in complex with g5-006 homo di-gluebody (126 kDa, Complex)
- Atp-dependent dna helicase q5 (49 kDa, Protein from Homo sapiens)
- Gluebody g5-006 (13 kDa, Protein from Lama glama)
- Di-gluebody g5-006 (Complex from Lama glama)
DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 - RECQL5 local refinement
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8rl6
Q-score: 0.22
Yi G, Mamalis D, Ye M, Carrique L, Fairhead M, Li H, Duerr K, Zhang P, Sauer DB, von Delft F, Davis BG, Gilbert RJC
To Be Published
- Atp-dependent dna helicase q5 (49 kDa, Protein from Homo sapiens)
- Local refinement of the recql5 part of recql5 homodimer assembled by g5-006 homo di-gluebody (126 kDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)