Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8dmh
Q-score: 0.515
Moon-Walker A, Zhang Z, Zyla DS, Buck TK, Li H, Diaz Avalos R, Schendel SL, Hastie KM, Crotty S, Saphire EO
Cell Chem Biol (2023) 30 pp. 403-411.e4 [ Pubmed: 36990092 DOI: doi:10.1016/j.chembiol.2023.03.005 ]
- Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody m28 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glycoprotein g1 (25 kDa, Protein from Lymphocytic choriomeningitis virus)
- 18.5c-m28 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Glycoprotein (Complex from Lymphocytic choriomeningitis mammarenavirus)
- Glycoprotein g2,cobalamin adenosyltransferase-like domain-containing protein trimerization tag (42 kDa, Protein from Lymphocytic choriomeningitis virus)
- 18.5c-m28 fab light chain (23 kDa, Protein from Homo sapiens)
- 18.5c-m28 fab light chain, 18.5c-m28 fab heavy chain (Complex from Homo sapiens)
Lymphocytic choriomeningitis virus glycoprotein
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8dmi
Q-score: 0.454
Moon-Walker A, Zhang Z, Zyla DS, Buck TK, Li H, Diaz Avalos R, Schendel SL, Hastie KM, Crotty S, Saphire EO
Cell Chem Biol (2023) 30 pp. 403-411.e4 [ Pubmed: 36990092 DOI: doi:10.1016/j.chembiol.2023.03.005 ]
- Glycoprotein g2,cobalamin adenosyltransferase-like domain-containing protein trimerization tag (42 kDa, Protein from Lymphocytic choriomeningitis virus)
- Lymphocytic choriomeningitis virus glycoprotein (Complex from Lymphocytic choriomeningitis mammarenavirus)
- Glycoprotein g1 (25 kDa, Protein from Lymphocytic choriomeningitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uds
Q-score: 0.403
Buck TK, Enriquez AS, Schendel SL, Zandonatti MA, Harkins SS, Li H, Moon-Walker A, Robinson JE, Branco LM, Garry RF, Saphire EO, Hastie KM
Mbio (2022) 13 pp. e0127822-e0127822 [ DOI: doi:10.1128/mbio.01278-22 Pubmed: 35730904 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 25.10c fab light chain (22 kDa, Protein from Homo sapiens)
- 25.10c fab heavy chain (24 kDa, Protein from Homo sapiens)
- Glycoprotein g2 (23 kDa, Protein from Lassa mammarenavirus)
- Lineage i lassa virus glycoprotein bound to fab 25.10c (350 kDa, Complex)
- Glycoprotein g1 (28 kDa, Protein from Lassa mammarenavirus)
Lineage I (Pinneo) Lassa virus glycoprotein bound to 18.5C-M30 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 7ul7
Q-score: 0.336
Buck TK, Enriquez AS, Schendel SL, Zandonatti MA, Harkins SS, Li H, Moon-Walker A, Robinson JE, Branco LM, Garry RF, Saphire EO, Hastie KM
Mbio (2022) 13 pp. e0127822-e0127822 [ DOI: doi:10.1128/mbio.01278-22 Pubmed: 35730904 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glycoprotein g2 (23 kDa, Protein from Lassa mammarenavirus)
- Lineage i (pinneo) lassa virus glycoprotein bound to 18.5c-m30 fab (350 kDa, Complex)
- 18.5c-m30 fab light chain (25 kDa, Protein from Homo sapiens)
- 18.5c-m30 fab heavy chain (26 kDa, Protein from Homo sapiens)
- Glycoprotein g1 (28 kDa, Protein from Lassa mammarenavirus)