Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 9bcx
Q-score: 0.133
Faull SV, Barbon M, Mossler A, Yuan Z, Bai L, Reuter LM, Riera A, Winkler C, Magdalou I, Peach M, Li H, Speck C
Nat Commun (2025) 16 pp. 14-14 [ Pubmed: 39747125 DOI: doi:10.1038/s41467-024-55479-1 ]
- Dna replication licensing factor mcm3 (107 kDa, Protein from Saccharomyces cerevisiae)
- Tah11 isoform 1 (68 kDa, Protein from Saccharomyces cerevisiae)
- Origin recognition complex subunit 6 (50 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm4 (105 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm2 (98 kDa, Protein from Saccharomyces cerevisiae)
- Origin recognition complex subunit 4 (60 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm7 (95 kDa, Protein from Saccharomyces cerevisiae)
- Origin recognition complex subunit 3 (72 kDa, Protein from Saccharomyces cerevisiae)
- Origin recognition complex subunit 1 (104 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Origin recognition complex subunit 2 (71 kDa, Protein from Saccharomyces cerevisiae)
- Orc-cdc6-mcm2-7-dsdna (Complex from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm6 (113 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm5 (86 kDa, Protein from Saccharomyces cerevisiae)
- Dna (39-mer) (12 kDa, DNA from synthetic construct)
- Dna (39-mer) (11 kDa, DNA from synthetic construct)
- Origin recognition complex subunit 5 (55 kDa, Protein from Saccharomyces cerevisiae)
- Cell division control protein 6 (58 kDa, Protein from Saccharomyces cerevisiae)
Human OGG1 bound to a 35-bp DNA with an 8-oxoG in the middle
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8vx4
Q-score: 0.358
You Q, Feng X, Cai Y, Baylin SB, Li H
Commun Biol (2024) 7 pp. 1202-1202 [ DOI: doi:10.1038/s42003-024-06919-7 Pubmed: 39341999 ]
- Dna (35-mer) (10 kDa, DNA from synthetic construct)
- Dna (35-mer) (10 kDa, DNA from synthetic construct)
- N-glycosylase/dna lyase (43 kDa, Protein from Homo sapiens)
- Complex of human ogg1 with a 35 bp dna duplex containing 8-oxog (Complex from Homo sapiens)
Nucleosome core particle containing an 8-oxoG damage site
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8vx5
Q-score: 0.493
You Q, Feng X, Cai Y, Baylin SB, Li H
Commun Biol (2024) 7 pp. 1202-1202 [ DOI: doi:10.1038/s42003-024-06919-7 Pubmed: 39341999 ]
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
- Histone h2a (18 kDa, Protein from Xenopus laevis)
- Complex of human ogg1 with a 35 bp dna duplex containing 8-oxog (Complex from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
- Histone h4 (13 kDa, Protein from Xenopus laevis)
Human OGG1 bound at the nucleosomal DNA entry site
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8vx6
Q-score: 0.424
You Q, Feng X, Cai Y, Baylin SB, Li H
Commun Biol (2024) 7 pp. 1202-1202 [ DOI: doi:10.1038/s42003-024-06919-7 Pubmed: 39341999 ]
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
- Histone h2a (18 kDa, Protein from Xenopus laevis)
- Complex of human ogg1 with a 35 bp dna duplex containing 8-oxog (Complex from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- N-glycosylase/dna lyase (43 kDa, Protein from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Dna (167-mer) (51 kDa, DNA from synthetic construct)
- Histone h4 (13 kDa, Protein from Xenopus laevis)
Cryo-EM structure of S. cerevisiae PolE-Ctf18-8-1-DNA
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tw9
Q-score: 0.438
Yuan Z, Georgescu R, Yao NY, Yurieva O, O'Donnell ME, Li H
Science (2024) 385 pp. eadk5901-eadk5901 [ Pubmed: 39088616 DOI: doi:10.1126/science.adk5901 ]
- Template dna (4 kDa, DNA from synthetic construct)
- Chromosome transmission fidelity protein 8 (15 kDa, Protein from Saccharomyces cerevisiae)
- Iron/sulfur cluster (351 Da, Ligand)
- Chromosome transmission fidelity protein 18 (3 kDa, Protein from Saccharomyces cerevisiae)
- Sister chromatid cohesion protein dcc1 (44 kDa, Protein from Saccharomyces cerevisiae)
- Primer dna (2 kDa, DNA from synthetic construct)
- Ctf18-rfc-pcna complex (Complex from Saccharomyces cerevisiae)
- Dna polymerase epsilon catalytic subunit a (255 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA-PolE-DNA complex
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8twa
Q-score: 0.349
Yuan Z, Georgescu R, Yao NY, Yurieva O, O'Donnell ME, Li H
Science (2024) 385 pp. eadk5901-eadk5901 [ Pubmed: 39088616 DOI: doi:10.1126/science.adk5901 ]
- Proliferating cell nuclear antigen (28 kDa, Protein from Saccharomyces cerevisiae)
- Template dna (4 kDa, DNA from synthetic construct)
- Ctf18-rfc-pcna-pole-dna complex (Complex from Saccharomyces cerevisiae)
- Chromosome transmission fidelity protein 8 (15 kDa, Protein from Saccharomyces cerevisiae)
- Replication factor c subunit 5 (39 kDa, Protein from Saccharomyces cerevisiae)
- Replication factor c subunit 3 (36 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Replication factor c subunit 4 (35 kDa, Protein from Saccharomyces cerevisiae)
- Chromosome transmission fidelity protein 18 (3 kDa, Protein from Saccharomyces cerevisiae)
- Sister chromatid cohesion protein dcc1 (44 kDa, Protein from Saccharomyces cerevisiae)
- Primer dna (2 kDa, DNA from synthetic construct)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Chromosome transmission fidelity protein 18 (84 kDa, Protein from Saccharomyces cerevisiae)
- Replication factor c subunit 2 (38 kDa, Protein from Saccharomyces cerevisiae)
- Dna polymerase epsilon catalytic subunit a (255 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of S. cerevisiae Ctf18-RFC-PCNA-DNA complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8twb
Q-score: 0.482
Yuan Z, Georgescu R, Yao NY, Yurieva O, O'Donnell ME, Li H
Science (2024) 385 pp. eadk5901-eadk5901 [ Pubmed: 39088616 DOI: doi:10.1126/science.adk5901 ]
- Template dna (5 kDa, DNA from synthetic construct)
- Replication factor c subunit 2 (38 kDa, Protein from Saccharomyces cerevisiae)
- Proliferating cell nuclear antigen (28 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Primer dna (5 kDa, DNA from synthetic construct)
- Replication factor c subunit 3 (36 kDa, Protein from Saccharomyces cerevisiae)
- Ctf18-rfc-pcna complex (Complex from Saccharomyces cerevisiae)
- Replication factor c subunit 4 (35 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Chromosome transmission fidelity protein 18 (30 kDa, Protein from Saccharomyces cerevisiae)
- Replication factor c subunit 5 (39 kDa, Protein from Saccharomyces cerevisiae)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
Bovine adult muscle nAChR resting state
Resolution: 2.09 Å
EM Method: Single-particle
Fitted PDBs: 9avv
Q-score: 0.658
Nature (2024) 632 pp. 1174-1180 [ DOI: doi:10.1038/s41586-024-07774-6 Pubmed: 39085615 ]
- Acetylcholine receptor subunit delta (56 kDa, Protein from Bos taurus)
- Acetylcholine receptor subunit epsilon (52 kDa, Protein from Bos taurus)
- Bovine muscle nicotinic acetylcholine receptor (Complex from Bos taurus)
- Acetylcholine receptor subunit beta (55 kDa, Protein from Bos taurus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Acetylcholine receptor subunit alpha (49 kDa, Protein from Bos taurus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toxin (6 kDa, Protein from synthetic construct)
Bovine fetal muscle nAChR resting state
Resolution: 2.14 Å
EM Method: Single-particle
Fitted PDBs: 9awk
Q-score: 0.634
Nature (2024) 632 pp. 1174-1180 [ DOI: doi:10.1038/s41586-024-07774-6 Pubmed: 39085615 ]
- Acetylcholine receptor subunit gamma (55 kDa, Protein from Bos taurus)
- Acetylcholine receptor subunit delta (56 kDa, Protein from Bos taurus)
- Bovine muscle nicotinic acetylcholine receptor (Complex from Bos taurus)
- Acetylcholine receptor subunit beta (55 kDa, Protein from Bos taurus)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Acetylcholine receptor subunit alpha (49 kDa, Protein from Bos taurus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toxin (6 kDa, Protein from synthetic construct)
Cryo-EM structure of human gamma-secretase in complex with Abeta43