Cryo-EM structure of the Cas9d-sgRNA-target DNA complex
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8zdr
Q-score: 0.541
To Be Published
- A protein (Complex from metagenome)
- Zinc ion (65 Da, Ligand)
- Dna (32-mer) (11 kDa, DNA from metagenome)
- Dna (5'-d(p*cp*gp*gp*gp*tp*cp*ap*ap*ap*tp*g)-3') (11 kDa, DNA from metagenome)
- Rna (144-mer) (51 kDa, RNA from metagenome)
- A protein (86 kDa, Protein from metagenome)
Cryo-EM structure of the Cas9d-sgRNA complex
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8zq9
Q-score: 0.47
To Be Published
- A protein (Complex from metagenome)
- Zinc ion (65 Da, Ligand)
- Rna (128-mer) (51 kDa, RNA from metagenome)
- A protein (86 kDa, Protein from metagenome)
Cryo-EM Structure of MILI(K852A)-piRNA-target (26-nt)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9ij4
Q-score: 0.474
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X, Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen EZ
Nature (2025) [ Pubmed: 39814893 DOI: doi:10.1038/s41586-024-08438-1 ]
- Mili(k852a)-pirna-target (26-nt) (Complex from Homo sapiens)
- Rna (26-mer) (8 kDa, RNA from Homo sapiens)
- Piwi-like protein 2 (109 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Rna (25-mer) (8 kDa, RNA from Homo sapiens)
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 9jmz
Q-score: 0.489
Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang Y, Chen J, Li Y, Jin X, Duan X, Zhang W, Bi Y, Jin R, Sun L, Wang N, Gao GF
Cell (2025) [ Pubmed: 39848246 DOI: doi:10.1016/j.cell.2025.01.019 ]
- Human-infecting bovine influenza h5n1 hemagglutinin complexed with avian receptor analog lsta (Complex from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 9jn0
Q-score: 0.518
Structure of chanoclavine synthase from Claviceps fusiformis
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 9jdb
Q-score: 0.633
Liu ZW, Wang T, Li X, Shen PP, Huang J-W, Chen C-C, Guo R-T
To Be Published
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Catalase easc (54 kDa, Protein from Claviceps fusiformis)
- Ergot alkaloid synthesis protein c (Complex from Claviceps fusiformis)
Structure of chanoclavine synthase from Claviceps fusiformis in complex with prechanoclavine
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 9jdc
Q-score: 0.693
Liu ZW, Wang T, Li X, Shen PP, Huang J-W, Chen C-C, Guo R-T
To Be Published
- Protoporphyrin ix containing fe (616 Da, Ligand)
- (2~{s})-2-(methylamino)-3-[4-[(1~{e})-3-methylbuta-1,3-dienyl]-1~{h}-indol-3-yl]propanoic acid (284 Da, Ligand)
- Catalase easc (54 kDa, Protein from Claviceps fusiformis)
- Ergot alkaloid synthesis protein c (Complex from Claviceps fusiformis)
Cryo-EM Structure of the 3HO-HCAR3-Gi complex
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8jef
Q-score: 0.517
Ye F, Pan X, Zhang Z, Xiang X, Li X, Zhang B, Ning P, Liu A, Wang Q, Gong K, Li J, Zhu L, Qian C, Chen G, Du Y
Cell Rep (2024) 43 pp. 114895-114895 [ Pubmed: 39427321 DOI: doi:10.1016/j.celrep.2024.114895 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Cryo-em structure of the apo hcar3-gi complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Hydroxycarboxylic acid receptor 3 (44 kDa, Protein from Homo sapiens)
- (3s)-3-hydroxyoctanoic acid (160 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
Cryo-EM structure of NRG1A(LRR) in complex with EDS1-SAG101-(ADPr-ATP)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8yn1
Q-score: 0.561
Huang S, Wang J, Song R, Jia A, Xiao Y, Sun Y, Wang L, Mahr D, Wu Z, Han Z, Li X, Parker JE, Chai J
Nature (2025) [ Pubmed: 39939760 DOI: doi:10.1038/s41586-024-08521-7 ]
- Probable disease resistance protein at5g66900 (46 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Senescence-associated carboxylesterase 101 (61 kDa, Protein from Arabidopsis thaliana)
- Ternary complex of nrg1a(lrr) with eds1-sag101-(adpr-atp) (Complex from Arabidopsis)
- Protein eds1 (70 kDa, Protein from Arabidopsis thaliana)
Cryo-EM Structure of MILI-piRNA-target (8-nt)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9ij0
Q-score: 0.417
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X, Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen EZ
Nature (2025) [ Pubmed: 39814893 DOI: doi:10.1038/s41586-024-08438-1 ]
- Rna (5'-r(p*gp*ap*up*gp*gp*up*ap*a)-3') (2 kDa, RNA from Homo sapiens)
- Rna (26-mer) (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Piwi-like protein 2 (109 kDa, Protein from Mus musculus)
- Mili-pirna-target (8-nt) (Complex from Homo sapiens)