Cryo-EM structure of DiCas7-11 in complex with crRNA
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8wm4
Q-score: 0.435
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ DOI: doi:10.1038/s41392-024-01821-4 Pubmed: 38735995 ]
- Crrna (38-mer) (12 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Binary complex of cas7-11 and crrna (Complex from Escherichia coli)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wmc
Q-score: 0.538
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ DOI: doi:10.1038/s41392-024-01821-4 Pubmed: 38735995 ]
- Chat domain-containing protein (88 kDa, Protein from Desulfonema ishimotonii)
- Ternary complex of cas7-11_crrna_tpr-chat (Complex from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Rna (38-mer) (12 kDa, RNA from Escherichia coli)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wmi
Q-score: 0.426
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ DOI: doi:10.1038/s41392-024-01821-4 Pubmed: 38735995 ]
- Binary complex of dicas7-11 mutant with crrna (Complex from Escherichia coli)
- Crrna (39-mer) (12 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8wml
Q-score: 0.522
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ DOI: doi:10.1038/s41392-024-01821-4 Pubmed: 38735995 ]
- Chat domain-containing protein (7 kDa, Protein from Desulfonema ishimotonii)
- Ternary complex of cas7-11-crrna bound to n-terminal of tpr-chat (Complex from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Crrna (38-mer) (12 kDa, RNA from Escherichia coli)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7yhw
Q-score: 0.516
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Omicron ba.2.12.1 rbd (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ace2 (Complex)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.2.12.1 rbd in complex with human ace2 (local refinement) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7yj3
Q-score: 0.468
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- Omicron ba.2 rbd (Complex)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme 2 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with human ace2 (local refinement) (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 7yv8
Q-score: 0.553
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- Spike glycoprotein (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with golden hamster ace2 (local refinement) (Complex)
- Omicron ba.2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Golden hamster angiotensin-converting enzyme 2 (Complex from Mesocricetus auratus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (68 kDa, Protein from Mesocricetus auratus)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yvu
Q-score: 0.484
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mouse angiotensin-converting enzyme 2 (Complex from Mus musculus)
- Omicron ba.2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with mouse ace2 (local refinement) (Complex)
- Processed angiotensin-converting enzyme 2 (68 kDa, Protein from Mus musculus)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with rat ACE2 (local refinement)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8gry
Q-score: 0.425
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- Omicron ba.2 rbd (Complex)
- Zinc ion (65 Da, Ligand)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rat angiotensin-converting enzyme 2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 omicron ba.2 rbd in complex with mouse ace2 (local refinement) (Complex from Rattus norvegicus)
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with human ACE2 (local refinement)
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8h06
Q-score: 0.566
Zhao Z, Xie Y, Bai B, Luo C, Zhou J, Li W, Meng Y, Li L, Li D, Li X, Li X, Wang X, Sun J, Xu Z, Sun Y, Zhang W, Fan Z, Zhao X, Wu L, Ma J, Li OY, Shang G, Chai Y, Liu K, Wang P, Gao GF, Qi J
Nat Commun (2023) 14 pp. 4405-4405 [ DOI: doi:10.1038/s41467-023-39942-z Pubmed: 37479708 ]
- Processed angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Omicron ba.4/5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sars-cov-2 omicron ba.4/5 rbd in complex with human ace2 (local refinement) (Complex)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)