The structure of Candida albicans Cdr1 in fluconazole-bound state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9iul
Q-score: 0.567
Peng Y, Lu Y, Sun H, Ma J, Li X, Han X, Fang Z, Tan J, Qiu Y, Qu T, Yin M, Yan Z
Nat Commun (2024) 15 pp. 7722-7722 [ DOI: doi:10.1038/s41467-024-52107-w Pubmed: 39242571 ]
- Pip2(20:4/18:0) (1 kDa, Ligand)
- Pleiotropic abc efflux transporter of multiple drugs cdr1 (170 kDa, Protein from Candida albicans SC5314)
- The cryo-em structure of candida albicans cdr1 in fluconazole-bound state (Complex from Candida albicans SC5314)
- 2-(2,4-difluorophenyl)-1,3-di(1h-1,2,4-triazol-1-yl)propan-2-ol (306 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8xlv
Q-score: 0.354
Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xm5
Q-score: 0.446
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xmg
Q-score: 0.443
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8xmt
Q-score: 0.399
SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 8xn2
Q-score: 0.355
Li L, Shi K, Gu Y, Xu Z, Shu C, Li D, Sun J, Cong M, Li X, Zhao X, Yu G, Hu S, Tan H, Qi J, Ma X, Liu K, Gao GF
Structure (2024) 32 pp. 1055-1067.e6 [ DOI: doi:10.1016/j.str.2024.06.012 Pubmed: 39013463 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron eg.5.1 rbd (receptor binding domain) in complex with human ace2 (angiotensin converting enzyme 2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8xn3
Q-score: 0.355
Li L, Shi K, Gu Y, Xu Z, Shu C, Li D, Sun J, Cong M, Li X, Zhao X, Yu G, Hu S, Tan H, Qi J, Ma X, Liu K, Gao GF
Structure (2024) 32 pp. 1055-1067.e6 [ DOI: doi:10.1016/j.str.2024.06.012 Pubmed: 39013463 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sars-cov-2 omicron hv.1 rbd (receptor binding domain) in complex with human ace2 (angiotensin converting enzyme 2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8xn5
Q-score: 0.371
Li L, Shi K, Gu Y, Xu Z, Shu C, Li D, Sun J, Cong M, Li X, Zhao X, Yu G, Hu S, Tan H, Qi J, Ma X, Liu K, Gao GF
Structure (2024) 32 pp. 1055-1067.e6 [ DOI: doi:10.1016/j.str.2024.06.012 Pubmed: 39013463 ]
- Sars-cov-2 omicron eg.5.1 spike protein(6p) in complex with human ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (136 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8xnf
Q-score: 0.317
Li L, Shi K, Gu Y, Xu Z, Shu C, Li D, Sun J, Cong M, Li X, Zhao X, Yu G, Hu S, Tan H, Qi J, Ma X, Liu K, Gao GF
Structure (2024) 32 pp. 1055-1067.e6 [ DOI: doi:10.1016/j.str.2024.06.012 Pubmed: 39013463 ]
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.2.86.1 spike protein(6p) in complex with human ace2 (angiotensin converting enzyme 2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8xnk
Q-score: 0.365
Li L, Shi K, Gu Y, Xu Z, Shu C, Li D, Sun J, Cong M, Li X, Zhao X, Yu G, Hu S, Tan H, Qi J, Ma X, Liu K, Gao GF
Structure (2024) 32 pp. 1055-1067.e6 [ DOI: doi:10.1016/j.str.2024.06.012 Pubmed: 39013463 ]
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Spike glycoprotein (136 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron hv.1 spike protein(6p) in complex with human ace2 (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)