Cryo-EM Structure of MILI(K852A)-piRNA-target (26-nt)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9ij4
Q-score: 0.474
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X, Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen EZ
Nature (2025) [ DOI: doi:10.1038/s41586-024-08438-1 Pubmed: 39814893 ]
- Rna (25-mer) (8 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Mili(k852a)-pirna-target (26-nt) (Complex from Homo sapiens)
- Rna (26-mer) (8 kDa, RNA from Homo sapiens)
- Piwi-like protein 2 (109 kDa, Protein from Mus musculus)
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ikm
Q-score: 0.422
Cryo-EM structure of Lactobacillus casei DdmE bound with guide and target
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 9iw3
Q-score: 0.438
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ Pubmed: 39448873 DOI: doi:10.1038/s41422-024-01042-y ]
- Dna (5'-d(p*tp*gp*ap*cp*gp*gp*cp*tp*cp*tp*ap*ap*tp*cp*t)-3') (4 kDa, DNA from Lacticaseibacillus)
- Ddme (83 kDa, Protein from Lacticaseibacillus)
- Magnesium ion (24 Da, Ligand)
- Lactobacillus casei ddme bound with guide and target (Complex from Lacticaseibacillus)
- Dna (5'-d(p*cp*tp*tp*gp*ap*tp*ap*cp*gp*ap*c)-3') (3 kDa, DNA from Lacticaseibacillus)
- Dna (25-mer) (7 kDa, DNA from Lacticaseibacillus)
Cryo-EM structure of Lactobacillus casei DdmD dimer bound with DNA
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 9ix4
Q-score: 0.483
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ Pubmed: 39448873 DOI: doi:10.1038/s41422-024-01042-y ]
- Lactobacillus casei ddmd bound with dna substrate (Complex from Lacticaseibacillus)
- Dna (5'-d(p*ap*tp*gp*ap*gp*tp*ap*tp*ap*tp*cp*c)-3') (3 kDa, DNA from Lacticaseibacillus)
- Ddmd (137 kDa, Protein from Lacticaseibacillus)
- Dna (5'-d(p*tp*ap*tp*gp*ap*gp*tp*ap*tp*ap*tp*cp*c)-3') (3 kDa, DNA from Lacticaseibacillus)
- Dna (5'-d(p*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3') (3 kDa, DNA from Lacticaseibacillus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of Lactobacillus casei DdmDE bound with DNA
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9ixm
Q-score: 0.464
Huang P, Yan P, Guo L, Fei W, Li Z, Liu J, Kong J, Yao Y, Lu M, Xiao Y, Chen M
Cell Res (2024) 34 pp. 873-876 [ Pubmed: 39448873 DOI: doi:10.1038/s41422-024-01042-y ]
- Dna (30-mer) (9 kDa, DNA from Lacticaseibacillus)
- Lactobacillus casei ddmde bound with dna (Complex from Lacticaseibacillus)
- Dna (5'-d(p*tp*gp*ap*cp*gp*gp*cp*tp*cp*tp*ap*ap*tp*cp*t)-3') (4 kDa, DNA from Lacticaseibacillus)
- Ddme (83 kDa, Protein from Lacticaseibacillus)
- Ddmd (137 kDa, Protein from Lacticaseibacillus)
- Magnesium ion (24 Da, Ligand)
- Dna (30-mer) (9 kDa, DNA from Lacticaseibacillus)
The structure of type III CRISPR-associated deaminase in complex cA6 and ATP, fully activated
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8z3p
Q-score: 0.42
Li Y, Li Z, Yan P, Hua C, Kong J, Wu W, Cui Y, Duan Y, Li S, Li G, Ji S, Chen Y, Zhao Y, Yang P, Hu C, Lu M, Chen M, Xiao Y
Science (2024) pp. eadr0393-eadr0393 [ Pubmed: 39666823 DOI: doi:10.1126/science.adr0393 ]
- Caad:ca6:atp 6:3:6 (Complex from Limisphaera ngatamarikiensis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine deaminase domain-containing protein (69 kDa, Protein from Limisphaera ngatamarikiensis)
- Magnesium ion (24 Da, Ligand)
- Rna (5'-r(p*ap*ap*ap*ap*ap*a)-3') (1 kDa, RNA from Limisphaera ngatamarikiensis)
- Zinc ion (65 Da, Ligand)