Li Y, Shao K, Li Z, Zhu K, Gan BK, Shi J, Xiao Y, Luo M
Nat Commun (2024) 15 pp. 7090-7090 [ DOI: doi:10.1038/s41467-024-51600-6 Pubmed: 39154050 ]
- Phosphate ion (94 Da, Ligand)
- Protein kinase domain-containing protein (100 kDa, Protein from Streptococcus pneumoniae)
- Dimeric structure of class iii lanthipeptide modification enzyme pnekc with one protomer in complex with substrate pnea and gtp (210 kDa, Complex from Streptococcus pneumoniae)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Pnea lp (1 kDa, Protein from Streptococcus pneumoniae)
Li Y, Shao K, Li Z, Zhu K, Gan BK, Shi J, Xiao Y, Luo M
Nat Commun (2024) 15 pp. 7090-7090 [ DOI: doi:10.1038/s41467-024-51600-6 Pubmed: 39154050 ]
- Phosphate ion (94 Da, Ligand)
- Sapb/amfs family lantipeptide (4 kDa, Protein from Streptococcus pneumoniae)
- Dimeric structure of class iii lanthipeptide modification pnekc with gsp and pnea bound to one protomer. (210 kDa, Complex from Streptococcus pneumoniae)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Protein kinase domain-containing protein (100 kDa, Protein from Streptococcus pneumoniae)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Cryo-EM structure of ComA bound to its mature substrate CSP peptide
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8k4b
Q-score: 0.297
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ DOI: doi:10.1038/s41467-023-42852-9 Pubmed: 37935699 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Coma (Complex from Streptococcus pneumoniae)
- Competence factor transporting atp-binding protein/permease coma (80 kDa, Protein from Streptococcus pneumoniae D39)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of nucleotide-bound ComA E647Q mutant with Mg2+
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8k7a
Q-score: 0.235
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ DOI: doi:10.1038/s41467-023-42852-9 Pubmed: 37935699 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Coma (Complex from Streptococcus pneumoniae)
- Magnesium ion (24 Da, Ligand)
- Transport/processing atp-binding protein coma (80 kDa, Protein from Streptococcus pneumoniae R6)
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8hf5
Q-score: 0.501
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
Nat Commun (2023) 14 pp. 7178-7178 [ DOI: doi:10.1038/s41467-023-42852-9 Pubmed: 37935699 ]
- Transport/processing atp-binding protein coma (80 kDa, Protein from Streptococcus pneumoniae D39)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Coma (Complex from Streptococcus pneumoniae D39)