Electron Microscopy Data Bank

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Structure of the mouse TRPC4 ion channel

Release date: Oct. 21, 2020
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 6jzo
Q-score: 0.499

Duan J, Li J, Zeng B, Chen G, Peng X, Zhang Y, Wang J, Clapham DE, Li Z, Zhang J

To Be Published

Sample:

Cholesterol hemisuccinate (486 Da, Ligand)
Short transient receptor potential channel 4 (87 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
Mouse trpc4 (Complex from Mus musculus)

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EMD-9615

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Cryo-EM structure of the receptor-activated TRPC5 ion channel

Release date: Aug. 7, 2019
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 6aei
Q-score: 0.484

Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J

Sci Adv (2019) 5 [ Pubmed: 31355338 DOI: doi:10.1126/sciadv.aaw7935 ]

Sample:

Short transient receptor potential channel 5 (88 kDa, Protein from Mus musculus)
Cholesterol hemisuccinate (486 Da, Ligand)
Mouse trpc5 (Complex from Mus musculus)
Sodium ion (22 Da, Ligand)
2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)

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EMD-6842

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Structure of RIP2 CARD domain

Release date: Nov. 14, 2018
Resolution: 4.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 5yrn
Q-score: 0.105

Gong Q, Long Z, Zhong FL, Teo DET, Jin Y, Yin Z, Boo ZZ, Zhang Y, Zhang J, Yang R, Bhushan S, Reversade B, Li Z, Wu B

Nat Commun (2018) 9 pp. 4993-4993 [ Pubmed: 30478312 DOI: doi:10.1038/s41467-018-07447-9 ]

Sample:

Active rip2 signaling complex (Cellular component from Homo sapiens)
Receptor-interacting serine/threonine-protein kinase 2 (12 kDa, Protein from Homo sapiens)

EMD-6909

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CryoEM structure of HPV33 L1-only VLP

Release date: Oct. 10, 2018
Resolution: 10.0 Å
EM Method: Single-particle

Wei M, Wang D, Li Z, Song S, Kong X, Mo X, Yang Y, He M, Li Z, Huang B, Lin Z, Pan H, Zheng Q, Yu H, Gu Y, Zhang J, Li S, Xia N

Emerg Microbes Infect (2018) 7 pp. 160-160 [ DOI: doi:10.1038/s41426-018-0158-2 Pubmed: 30254257 ]

Sample:

Human papillomavirus type 33 (Virus from Human papillomavirus type 33)

EMD-6910

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CryoEM structure of HPV58 L1-only VLP

Release date: Oct. 10, 2018
Resolution: 12.5 Å
EM Method: Single-particle

Wei M, Wang D, Li Z, Song S, Kong X, Mo X, Yang Y, He M, Li Z, Huang B, Lin Z, Pan H, Zheng Q, Yu H, Gu Y, Zhang J, Li S, Xia N

Emerg Microbes Infect (2018) 7 pp. 160-160 [ DOI: doi:10.1038/s41426-018-0158-2 Pubmed: 30254257 ]

Sample:

Human papillomavirus type 58 (Virus from Human papillomavirus type 58)

EMD-6918

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CryoEM structure of HPV52 L1-only VLP

Release date: Oct. 10, 2018
Resolution: 7.0 Å
EM Method: Single-particle

Wei M, Wang D, Li Z, Song S, Kong X, Mo X, Yang Y, He M, Li Z, Huang B, Lin Z, Pan H, Zheng Q, Yu H, Gu Y, Zhang J, Li S, Xia N

Emerg Microbes Infect (2018) 7 pp. 160-160 [ DOI: doi:10.1038/s41426-018-0158-2 Pubmed: 30254257 ]

Sample:

Human papillomavirus type 52 (Virus from Human papillomavirus type 52)

EMD-6919

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CryoEM structure of HPV45 L1-only VLP

Release date: Oct. 10, 2018
Resolution: 9.0 Å
EM Method: Single-particle

Wei M, Wang D, Li Z, Song S, Kong X, Mo X, Yang Y, He M, Li Z, Huang B, Lin Z, Pan H, Zheng Q, Yu H, Gu Y, Zhang J, Li S, Xia N

Emerg Microbes Infect (2018) 7 pp. 160-160 [ DOI: doi:10.1038/s41426-018-0158-2 Pubmed: 30254257 ]

Sample:

Human papillomavirus type 45 (Virus from Human papillomavirus type 45)

EMD-9617

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Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1

Release date: Aug. 8, 2018
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6agf
Q-score: 0.526

Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N

Science (2018) 362 [ DOI: doi:10.1126/science.aau2486 Pubmed: 30190309 ]

Sample:

[(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
(3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
Human sodium channel subunit beta-1 (Complex from Homo sapiens)
Human sodium channel protein type 4 subunit alpha (Complex from Homo sapiens)
Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
Complex of human sodium channel protein type 4 subunit alpha and human sodium channel subunit beta-1 (200 kDa, Complex)
Sodium channel protein type 4 subunit alpha (212 kDa, Protein from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)

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EMD-6901

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Structure of the mouse TRPC4 ion channel

Release date: April 18, 2018
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 5z96
Q-score: 0.481

Duan J, Li J, Zeng B, Chen GL, Peng X, Zhang Y, Wang J, Clapham DE, Li Z, Zhang J

Nat Commun (2018) 9 pp. 3102-3102 [ DOI: doi:10.1038/s41467-018-05247-9 Pubmed: 30082700 ]

Sample:

Cholesterol hemisuccinate (486 Da, Ligand)
Short transient receptor potential channel 4 (87 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
Mouse trpc4 (Complex from Mus musculus)

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